Diferencia entre revisiones de «Template:Appendicitis Antibiotics»
| Línea 17: | Línea 17: | ||
====Complicated Appendicitis==== | ====Complicated Appendicitis==== | ||
''Defined as perforation, abscess, or phlegmon'' | |||
'''Options:''' | '''Options:''' | ||
*[[Metronidazole]] 50mg IV q8hrs + | *[[Metronidazole]] 50mg IV q8hrs + | ||
Revisión del 20:16 14 abr 2015
Coverage should extend to E. coli, Klebsiella, Proteus, and Bacteroides (an anaerobe)
Adult Simple Appendicitis
Antibiotic prophylaxis should be coordinated with surgical consult Options:
- Cefoxitin 2g IV q6 hours OR
- Cefotetan 2g IV q12 hours OR
- Moxifloxacin 400mg IV once daily
- Ertapenem 1g IV once daily
Pediatric Simple Appendicitis
Options:
- Cefoxitin 40mg/kg IV q6 hours
- Cefotetan 40mg/kg IV q12 hours
- Gentamicin 2.5mg/kg IV q8hrs +
- Metronidazole 7.5mg/kg IV 16hrs OR
- Clindamycin 10mg/kg IV q8hrs
Complicated Appendicitis
Defined as perforation, abscess, or phlegmon
Options:
- Metronidazole 50mg IV q8hrs +
- Cefepime 50mg/kg IV q12hrs OR
- Ciprofloxacin 400mg IV q12hrs OR
- Levofloxacin 750mg IV q24hrs
- Aztreonam 30mg/kg IV q8hrs
- Imipenem/Cilastatin 25mg/kg IV q6hrs (max 500mg)
- Meropenem 20mg/kg IV q8hrs (max 1g)
- Piperacillin/Tazobactam 100mg/kg (max 4.5g) IV q8hrs
Cautious use should be applied to use of fluoroquinolones in complicated pediatric appendicitis due to the risk of tendon injury