Diferencia entre revisiones de «Template:Vasopressor table»
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! Pressor!! Initial Dose !! Max Dose !! Cardiac Effect !! BP Effect !! Arrhythmias !! Special Notes | ! Pressor!! Initial Dose !! Max Dose !! Cardiac Effect !! BP Effect !! [[Arrhythmias]] !! Special Notes | ||
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| [[Dobutamine]] || 2.5mcg/kg/min || 10-40 mcg/kg/min || mainly inotrope (ß1) || alpha effect minimal || Some HR(ß1) increase. Also Increase SA and AV node fx || Debut Research 1979<ref>Edmund H. Sonnenblick, M.D., William H. Frishman, M.D., and Thierry H. LeJemtel, M.D. Dobutamine: A New Synthetic Cardioactive Sympathetic Amine</ref> Isoproterenol has most Β2 vasodilatory and Β1 HR effects | | [[Dobutamine]] || 2.5mcg/kg/min || 10-40 mcg/kg/min || mainly inotrope (ß1) || alpha effect minimal || Some HR(ß1) increase. Also Increase SA and AV node fx || Debut Research 1979<ref>Edmund H. Sonnenblick, M.D., William H. Frishman, M.D., and Thierry H. LeJemtel, M.D. Dobutamine: A New Synthetic Cardioactive Sympathetic Amine</ref> Isoproterenol has most Β2 vasodilatory and Β1 HR effects | ||
Revisión del 07:23 18 feb 2015
Vasopressors
| Pressor | Initial Dose | Max Dose | Cardiac Effect | BP Effect | Arrhythmias | Special Notes |
|---|---|---|---|---|---|---|
| Dobutamine | 2.5mcg/kg/min | 10-40 mcg/kg/min | mainly inotrope (ß1) | alpha effect minimal | Some HR(ß1) increase. Also Increase SA and AV node fx | Debut Research 1979[1] Isoproterenol has most Β2 vasodilatory and Β1 HR effects |
| Dopamine | 2mcg/kg/min | 20-50 mcg/kg/min | β1 and NorEpi release | α effects if > 20mcg/kg/min | Arrhythmogenic from β1 effects | More adverse events when used in shock compared to Norepi[2] |
| Norepinephrine | 8-12mcg/min | 30 mcg/min | β1 direct effect | β1 and α1,2 effects | Less arrhythmias than Dopamine[2] | Increases MAP, coronary perfusion pressure, little β2 effects. |
| Milrinone | 50mcg/kg x 10 min | 0.375-75mcg/kg/min | Direct influx of Ca2+ channels | Smooth muscle vasodilator | PDE Inhibitor which increases Ca2+ uptake by sarcolemma. No venodilatory activity | |
| Phenylephrine | 100-180mcg/min then 40-60mcg/min | 0.4-9 mcg/kg/min | Alpha agonist | Long half life | ||
| Vasopressin | Fixed Dose | 0.4 U/min | unknown | increases via ADH peptide | should not be titrated due to ischemic effects |