Diferencia entre revisiones de «Clozapine»
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== | ==General== | ||
*Atypical antipsychotic | *Type: Atypical antipsychotic | ||
*Dosage Forms: | |||
*Common Trade Names: | |||
==Adult Dosing== | |||
*Controls positive and negative symptoms of psychotic disorders | *Controls positive and negative symptoms of psychotic disorders | ||
*Used for schizophrenia | *Used for schizophrenia | ||
| Línea 7: | Línea 11: | ||
**Borderline personality disorder | **Borderline personality disorder | ||
== | ==Pediatric Dosing== | ||
*QT | |||
*Myocarditis | ==Special Populations== | ||
*Agranulocytosis in 1%–2% of patients during initial treatment 3 months | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | ||
*Lactation: | |||
*Renal Dosing | |||
**Adult | |||
**Pediatric | |||
*Hepatic Dosing | |||
**Adult | |||
**Pediatric | |||
==Contraindications== | |||
*Allergy to class/drug | |||
==Adverse Reactions== | |||
*[[QT prolongation]] | |||
*[[Myocarditis]] | |||
*[[Agranulocytosis]] in 1%–2% of patients during initial treatment 3 months | |||
**Highest ~3 months into treatment and then decreases | **Highest ~3 months into treatment and then decreases | ||
*Other potential side effects: | *Other potential side effects: | ||
| Línea 19: | Línea 38: | ||
*"Increased mortality in elderly patients with dementia-related psychosis"<ref>"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.</ref> | *"Increased mortality in elderly patients with dementia-related psychosis"<ref>"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.</ref> | ||
==Also | ==Pharmacology== | ||
*Half-life: | |||
*Metabolism: | |||
*Excretion: | |||
*Mechanism of Action: | |||
==See Also== | |||
*[[Schizophrenia]] | *[[Schizophrenia]] | ||
*[[Bipolar disorder]] | *[[Bipolar disorder]] | ||
| Línea 28: | Línea 53: | ||
*Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162 | *Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162 | ||
*"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09. | *"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09. | ||
<references/> | |||
[[Category:Drugs]] | |||
[[Category:Psych]] | [[Category:Psych]] | ||
Revisión del 18:32 9 feb 2015
General
- Type: Atypical antipsychotic
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Controls positive and negative symptoms of psychotic disorders
- Used for schizophrenia
- Off label use:
- Bipolar disorder
- Borderline personality disorder
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- QT prolongation
- Myocarditis
- Agranulocytosis in 1%–2% of patients during initial treatment 3 months
- Highest ~3 months into treatment and then decreases
- Other potential side effects:
- Dyslipidemia
- Diabetes
- Decreased seizure threshold
- "Other adverse cardiovascular and respiratory effects" [1]
- "Increased mortality in elderly patients with dementia-related psychosis"[2]
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162
- "Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.