Diferencia entre revisiones de «HIV post-exposure prophylaxis»

(Created page with "1) Td 2) Hepatitis B PEP for non-vaccinated -Hepatitis B immunoglobulin and/or vaccine 3) Source labs -Rapid HIV, hep pannel, RPR? 4) Exposed labs -Rapid HIV...")
 
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1) Td
==Workup==
#Td
#Hepatitis B PEP for non-vaccinated
##Hepatitis B immunoglobulin and/or vaccine
#Source labs
##Rapid HIV, hep pannel, RPR?
#Exposed labs
##Rapid HIV, hep pannel, RPR?
#Consider HIV PEP
##CBC, C7, LFTs, Icon if considering HIV PEP


2) Hepatitis B PEP for non-vaccinated
^Currently no PEP for Hep C


    -Hepatitis B immunoglobulin and/or vaccine
==HIV PEP==
 
*~79% transmission reduction
3) Source labs
*Initiate ASAP (goal = 1-2 hours)
 
*>36 hours: normally deferred, unless particularly high risk
    -Rapid HIV, hep pannel, RPR?
*Common side-effects = constitutional, gastrointestinal
 
4) Exposed labs
 
    -Rapid HIV, hep pannel, RPR?
 
5) Consider HIV PEP
 
    -CBC, C7, LFTs, Icon if considering HIV PEP
 
*Currently no PEP for Hep C
 
 
HIV PEP
 
~79% transmission reduction
 
Initiate ASAP (goal = 1-2 hours)
 
>36 hours: normally deferred, unless particularly high risk
 
Common side-effects = constitutional, gastrointestinal
 


CDC website lists specific regimens
CDC website lists specific regimens
#Basic
##Exposures for which there is a recognized transmission risk
##4 week, 2 drug regimen (normally zidovudine and lamivudine)
#Expanded
##High risk exposures
##Basic regimen + protease inhibitor (e.g. indinavir or nelfinavir)


1) Basic
==HIGH RISK==
 
-Exposures for which there is a recognized transmission risk
 
-4 week, 2 drug regimen (normally zidovudine and lamivudine)
 
2) Expanded
 
-High risk exposures
 
-Basic regimen + protease inhibitor (e.g. indinavir or nelfinavir)
 
 
HIGH RISK
 
Source
Source
 
#Symptomatic HIV/AIDS
-Symptomatic HIV/AIDS
#Acute seroconversion
 
#High viral load
-Acute seroconversion
 
-High viral load


Exposure
Exposure
#Deep injuries
#Visible blood on device
#Injuries sustained placing a catheter in a vein/artery


-Deep injuries
==Source==
 
-Visible blood on device
 
-Injuries sustained placing a catheter in a vein/artery
 
 
8/07 DONALDSON
8/07 DONALDSON


[[Category:ID]]
[[Category:ID]]

Revisión del 04:40 28 mar 2011

Workup

  1. Td
  2. Hepatitis B PEP for non-vaccinated
    1. Hepatitis B immunoglobulin and/or vaccine
  3. Source labs
    1. Rapid HIV, hep pannel, RPR?
  4. Exposed labs
    1. Rapid HIV, hep pannel, RPR?
  5. Consider HIV PEP
    1. CBC, C7, LFTs, Icon if considering HIV PEP

^Currently no PEP for Hep C

HIV PEP

  • ~79% transmission reduction
  • Initiate ASAP (goal = 1-2 hours)
  • >36 hours: normally deferred, unless particularly high risk
  • Common side-effects = constitutional, gastrointestinal

CDC website lists specific regimens

  1. Basic
    1. Exposures for which there is a recognized transmission risk
    2. 4 week, 2 drug regimen (normally zidovudine and lamivudine)
  2. Expanded
    1. High risk exposures
    2. Basic regimen + protease inhibitor (e.g. indinavir or nelfinavir)

HIGH RISK

Source

  1. Symptomatic HIV/AIDS
  2. Acute seroconversion
  3. High viral load

Exposure

  1. Deep injuries
  2. Visible blood on device
  3. Injuries sustained placing a catheter in a vein/artery

Source

8/07 DONALDSON

Obtenido de «https://www.wikem.org/w/index.php?title=HIV_post-exposure_prophylaxis&oldid=1689»