Diferencia entre revisiones de «Levamisole toxicity»
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==Management== | ==Management== | ||
*Aggressive supportive care | |||
==Disposition== | ==Disposition== | ||
Revisión del 03:38 29 oct 2014
Background
- an antihelminthic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives that has been withdrawn from the U.S. and Canadian markets, due to the risk of serious side effects
- Increasingly used as a cutting agent in cocaine sold around the globe
- Results in Levamisole induced necrosis syndrome[1]
Clinical Features
- agranulocytosis
- neutropenia
- levamisole induced necrosis syndrome
- Necrotic patches anywhere on skin (especially ears and legs)
Differential Diagnosis
Workup
Management
- Aggressive supportive care