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==Comments==
==Comments==
==Indications by Condition==
''The following table is automatically generated from disease/condition pages across WikEM.''
{{#ask:[[Has DrugName::Misoprostol]]
|?Has Indication=Indication
|?Has Dose=Dose
|?Has Context=Context
|?Has Route=Route
|?Has Population=Population
|format=broadtable
|headers=plain
|mainlabel=-
|sort=Has Indication
|limit=50
}}


==See Also==
==See Also==

Revisión del 17:45 20 mar 2026

General

  • Type: Prostaglandin
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names: Cytotec

Adult Dosing

Postpartum hemorrhage

  • Second Line therapy and can be administered sublingually, orally, vaginally, and rectally.[1]
  • 1,000 mcg administered rectally
  • 800 mcg PO

Pediatric Dosing

Special Populations

Contraindications

  • Allergy to class/drug
  • Pregnancy (when used to treat ulcers)

Adverse Reactions

Serious

  • Anaphylaxis
  • Dysrhythmia, MI
  • GI bleed
  • Uterine rupture
  • Thromboembolic disorder

Common

  • Diarrhea, abdominal pain, flatulence, nausea
  • Headache
  • Anemia
  • Chest pain

Pharmacology

  • Half-life: 20-40min
  • Metabolism: Hepatic
  • Excretion:
  • Mechanism of Action: Synthetic prostaglandin E analogue

Comments

Indications by Condition

The following table is automatically generated from disease/condition pages across WikEM.

IndicationDoseContextRoutePopulation
First trimester abortion800mcg vaginally, repeat once in 7 days if no responseMedical management of early pregnancy loss (<12 weeks)VaginalAdult
Postpartum hemorrhage600 mcg SL or 1000 mcg PR2nd line uterotonicSL/PRAdult

See Also

References

  1. Mousa HA, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2003;(1):CD003249.