Diferencia entre revisiones de «Metoprolol»
Sin resumen de edición |
|||
| Línea 17: | Línea 17: | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: | *Lactation: | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: No adjustment necessary | ||
**Pediatric: No adjustment necessary | |||
**Pediatric | |||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: Not defined however consider reduced dose due to hepatic metabolism | ||
**Pediatric: Not defined however consider reduced dose due to hepatic metabolism | |||
**Pediatric | |||
==Contraindications== | ==Contraindications== | ||
| Línea 65: | Línea 61: | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:Cardiology]] | |||
Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. | Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. | ||
Revisión del 23:26 22 sep 2019
General
- Type: Beta blockers
- Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable
- Common Trade Names: Lopressor
Adult Dosing
Hypertension
- 50-200 mg PO bid
CHF
- 12.5-100 mg PO bid
Migraine prophylaxis
- 25-100 mg PO bid
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation:
- Renal Dosing
- Adult: No adjustment necessary
- Pediatric: No adjustment necessary
- Hepatic Dosing
- Adult: Not defined however consider reduced dose due to hepatic metabolism
- Pediatric: Not defined however consider reduced dose due to hepatic metabolism
Contraindications
- Allergy to class/drug
- Sinus bradycardia
- AV blocks
- decompensated acute CHF
- cardiogenic shock
- hypotension
Adverse Reactions
Serious
- CHF
- bradycardia
- AV block
- bronchospasm
Common
- fatigue
- dizziness
- depression
- dyspnea
Pharmacology
- Half-life: 3-7 hours
- Metabolism: Liver
- Excretion: Renal
- Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist
See Also
References
Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.