Diferencia entre revisiones de «Mucormycosis»
Sin resumen de edición |
Sin resumen de edición |
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#CNS | #CNS | ||
== | ==Clinical Features== | ||
Rhinocerebral: mimics acute bacterial sinusitis, however a much more rapid, extensive expansion of the fungus to the surrounding anatomy is classic | Rhinocerebral: mimics acute bacterial sinusitis, however a much more rapid, extensive expansion of the fungus to the surrounding anatomy is classic | ||
| Línea 21: | Línea 21: | ||
#Headache | #Headache | ||
== | ==Differential Diagnosis== | ||
== | |||
==Diagnostic Evaluation== | |||
*Can be clinical diagnosis | |||
*CT scan of sinuses with IV contrast can assist with diagnosis | |||
==Management== | |||
*Emergent ENT consult for OR debridement (definitive treatment) | |||
*Start Amphotericin B 1mg/kg IV | |||
*Aggressive resuscitation, airway management, and supportive care while in ED. | |||
==Prognosis== | ==Prognosis== | ||
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*[[Fungal Infections]] | *[[Fungal Infections]] | ||
==External Links== | |||
==References== | |||
<references/> | |||
[[Category:ENT]] | |||
[[Category:ID]] | [[Category:ID]] | ||
Revisión del 04:30 8 sep 2015
Background
- Infection of fungal hyphae in immunocompromised hosts
- DM
- HIV
- Neutropenic
Locations
- Most commonly affects paranasal sinuses (rhinocerebral mucormycosis)
- Pulmonary
- GI
- CNS
Clinical Features
Rhinocerebral: mimics acute bacterial sinusitis, however a much more rapid, extensive expansion of the fungus to the surrounding anatomy is classic
Can spread to orbits, oropharynx, nasopharynx, brain, nearby vasculature leading to:
- Vision changes
- Nasopharyngeal and oropharyngeal ulceration or eschars
- Facial edema, pain
- Cranial nerve deficits
- Headache
Differential Diagnosis
Diagnostic Evaluation
- Can be clinical diagnosis
- CT scan of sinuses with IV contrast can assist with diagnosis
Management
- Emergent ENT consult for OR debridement (definitive treatment)
- Start Amphotericin B 1mg/kg IV
- Aggressive resuscitation, airway management, and supportive care while in ED.
Prognosis
Mortality 30-90%