Diferencia entre revisiones de «Systemic lupus erythematosus»
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==Clinical Features== | ==Clinical Features== | ||
'''Diagnostic Criteria:''' | '''Diagnostic Criteria:''' | ||
4 out of 11 of the following: | |||
#Malar rash | |||
#Discoid rash | |||
#Photosensitivity | |||
#Oral ulcers | |||
#Arthritis (polyarticular) | |||
#Serositis (Pericarditis or pleuritis) | |||
#Renal disorder (renal failure, protenuria, casts) | |||
#Neurologic or psychotic symptoms | |||
#Hematologic (anemia, thrombocytopenia, or leukopenia) | |||
#Immunologic (+antibofy testing) | |||
#ANA (positive ANA) | |||
'''New Presentations''' | '''New Presentations''' | ||
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*[[DIC]] | *[[DIC]] | ||
==''' | ==Workup== | ||
'''Undiagnosed''' | |||
*CBC | *CBC | ||
*Chem 10 | *Chem 10 | ||
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*ESR | *ESR | ||
*UA | *UA | ||
*Bedside echo if ill | *Bedside echo if ill or hypotensive | ||
'''Flair''' | |||
*Bedside echo if ill or hypotensive | *Bedside echo if ill or hypotensive | ||
*CBC | *CBC | ||
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==Management== | ==Management== | ||
*Steroids | |||
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[[Lupus Anticoagulant]] | [[Lupus Anticoagulant]] | ||
[[Pericarditis]] | [[Pericarditis]] | ||
[[Pericardial Effusion and Tamponade]] | |||
[[Acute Renal Failure]] | [[Acute Renal Failure]] | ||
[[Adrenal Crisis]] | [[Adrenal Crisis]] | ||
Revisión del 19:53 25 mar 2014
Background
- Autoimmune disorder
Epidemiology
- Femaile:Male 10:1
- More common in African Americans
Clinical Features
Diagnostic Criteria: 4 out of 11 of the following:
- Malar rash
- Discoid rash
- Photosensitivity
- Oral ulcers
- Arthritis (polyarticular)
- Serositis (Pericarditis or pleuritis)
- Renal disorder (renal failure, protenuria, casts)
- Neurologic or psychotic symptoms
- Hematologic (anemia, thrombocytopenia, or leukopenia)
- Immunologic (+antibofy testing)
- ANA (positive ANA)
New Presentations
Flairs
Differential Diagnosis
- Rheumatoid arthritis
- Sjogren's syndrome
- Dermatomyositis
- Polymyositis
- Stevens-Johnson syndrome
- Toxic Epidermal Necrolysis
- Septic arthritis
- Lyme disease
- Vasculitis
- Acute Rheumatic Fever
- Toxic Shock Syndrome
- TTP
- ITP
- DIC
Workup
Undiagnosed
- CBC
- Chem 10
- ANA
- ESR
- UA
- Bedside echo if ill or hypotensive
Flair
- Bedside echo if ill or hypotensive
- CBC
Management
- Steroids
Disposition
See Also
Arthritis Fever and Rash Lupus Anticoagulant Pericarditis Pericardial Effusion and Tamponade Acute Renal Failure Adrenal Crisis
Sources
- Rosen's
- Up to date