Diferencia entre revisiones de «Trimethoprim-Sulfamethoxazole DS»
| Línea 37: | Línea 37: | ||
==Pregnancy/Lactation== | ==Pregnancy/Lactation== | ||
*Pregnancy: | *Pregnancy: D | ||
*Lactation: | *Lactation: ? | ||
==See Also== | ==See Also== | ||
Revisión del 15:38 24 feb 2014
General
- Type: Sulfonamide
- Dosage Forms: 160/800
- Common Trade Names: Bactrim DS
Adult Dosing
General
1 tab (160mg TMP) PO Q12h
PCP Prophylaxis
80-160mg TMP PO daily
PCP Treatment
15-20 mg/kg/day TMP PO divided q6-8h x 21 days
Pediatric Dosing
General (>2mo)
- Mild-mod infection
- 4-5 mg/kg TMP PO q12hr
- Severe infection
- 15-20 mg/kg/dy TMP PO divided q6-8h
Contraindications
- Allergy to class/drug
- <2 months of age (except as PCP prophylaxis)
- sig hepatic impairment
- megaloblastic anemia or folate deficiency
- G6PD deficiency
Adverse Reactions
Pharmacology
- Half-life: 6-12h (20-50h ESRD)
- Metabolism:
- Excretion:
- Mechanism of Action: Bactericidal
Pregnancy/Lactation
- Pregnancy: D
- Lactation: ?