Diferencia entre revisiones de «Raltegravir»
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==Administration== | ==Administration== | ||
*Type: | *Type: Antiretroviral, Integrase inhibitor | ||
*Dosage Forms: | *Dosage Forms: 400 mg, 600 mg tablet | ||
*Routes of Administration: | *Routes of Administration: PO | ||
*Common Trade Names: | *Common Trade Names: Isentress | ||
==Adult Dosing== | ==Adult Dosing== | ||
*Treatment-naive: | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
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==Special Populations== | ==Special Populations== | ||
*[[Drug pregnancy categories|Pregnancy Rating]]: | *[[Drug pregnancy categories|Pregnancy Rating]]: C | ||
*Lactation risk: | *Lactation risk: Unknown | ||
===Renal Dosing=== | ===Renal Dosing=== | ||
* | **Mild to Moderate renal disease: No dosage adjustment necessary | ||
* | **ESRD on HD: Dose after dialysis on dialysis days | ||
===Hepatic Dosing=== | ===Hepatic Dosing=== | ||
No dosage adjustment necessary | |||
==Contraindications== | ==Contraindications== | ||
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*[[Stevens-Johnson Syndrome]] | |||
*Anaphylaxis | |||
*Myopathy/[[Rhabdomyolysis]] | |||
===Common=== | ===Common=== | ||
*Hepatic- increased transaminases | |||
==Pharmacology== | ==Pharmacology== | ||
Revisión del 06:47 19 mar 2018
Administration
- Type: Antiretroviral, Integrase inhibitor
- Dosage Forms: 400 mg, 600 mg tablet
- Routes of Administration: PO
- Common Trade Names: Isentress
Adult Dosing
- Treatment-naive:
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation risk: Unknown
Renal Dosing
- Mild to Moderate renal disease: No dosage adjustment necessary
- ESRD on HD: Dose after dialysis on dialysis days
Hepatic Dosing
No dosage adjustment necessary
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Stevens-Johnson Syndrome
- Anaphylaxis
- Myopathy/Rhabdomyolysis
Common
- Hepatic- increased transaminases
Pharmacology
- Half-life:
- Metabolism:
- Excretion: