Diferencia entre revisiones de «Chlorate toxicity»
Sin resumen de edición |
(Text replacement - "==Diagnosis==" to "==Evaluation==") |
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| Línea 16: | Línea 16: | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
== | ==Evaluation== | ||
*Based on clinical history and presence of methemoglobinemia | *Based on clinical history and presence of methemoglobinemia | ||
*No specific levels are available | *No specific levels are available | ||
Revisión del 23:10 20 ago 2017
Background
- Potassium Chlorate, Barium Chlorate, and Sodium Chlorate are still in use today
- Fireworks, match heads, and weed killers
Mechanism of Toxicity
- Oxidizers and attackers of sulfhydryl groups
- Cause methemoglobin formation
Clinical Presentation
Differential Diagnosis
Evaluation
- Based on clinical history and presence of methemoglobinemia
- No specific levels are available
Management
- Activated charcoal IS recommended
- Methylene blue for methemoglobinemia (1-2 mg/kg of 1% solution)
- Sodium thiosulfate IV may inactivate chlorate ions (anecdotal)
- Hemodialysis
- Supportive Care
Disposition
External Links
References
Olson, K. Poisoning and Drug Overdose, 1999.