Diferencia entre revisiones de «Template:Pertussis Antibiotics»
(Add pediatric Clarithromycin and Erythromycin dosing)
 
(No se muestran 3 ediciones intermedias de 2 usuarios)
Línea 2: Línea 2:
*A reasonable guideline is to treat persons aged >1 year within 3 weeks of cough onset and infants aged <1 year and pregnant women (especially near term) within 6 weeks of cough onset. <ref>CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html</ref>
*A reasonable guideline is to treat persons aged >1 year within 3 weeks of cough onset and infants aged <1 year and pregnant women (especially near term) within 6 weeks of cough onset. <ref>CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html</ref>
*TMP--SMZ should not be administered to pregnant women, nursing mothers, or infants aged <2 months.<ref> CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm</ref>
*TMP--SMZ should not be administered to pregnant women, nursing mothers, or infants aged <2 months.<ref> CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm</ref>
*The following regemins are for active disease or postexposure prophylaxis. If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.
*The following regemins are for active disease or postexposure prophylaxis. If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.
 
====< 1 month old====
====< 1 month old====
''Same antibiotics for active disease and postexposure prophylaxis''
''Same antibiotics for active disease and postexposure prophylaxis''
*[[Azithromycin]] 10mg/kg (max 500mg/day) daily x 5 days
*{{AntibioticDose|disease=Pertussis|drug=Azithromycin|dose=10mg/kg (max 500mg/day) daily x 5 days|context=<1 month old|population=Pediatric}}
 
====>1 month old====
====>1 month old====
*[[Azithromycin]] 10mg/kg (max 500mg/day) daily x 5 days
*{{AntibioticDose|disease=Pertussis|drug=Azithromycin|dose=10mg/kg (max 500mg/day) daily x 5 days|context=>1 month old|population=Pediatric}}
**if > 6 months old then day 2-5 of treatment should be reduced to 5mg/kg (250mg/day max)
**if > 6 months old then day 2-5 of treatment should be reduced to 5mg/kg (250mg/day max)
*[[TMP/SMX]] 4mg/kg PO BID daily for 14 days (if > 2 months old)
*{{AntibioticDose|disease=Pertussis|drug=TMP/SMX|dose=4mg/kg PO BID daily for 14 days|context=>1 month old (if >2mo)|population=Pediatric}} (if > 2 months old)
 
 
*{{AntibioticDose|disease=Pertussis|drug=Clarithromycin|dose=>6 months: 7.5mg/kg PO BID x 7 days (max 500mg/dose)|context=>1 month old|population=Pediatric}}
*{{AntibioticDose|disease=Pertussis|drug=Erythromycin|dose=10mg/kg PO QID x 14 days (max 2g/day)|context=>1 month old|population=Pediatric}}
 
====Adults====
====Adults====
''andy of the following antibiotics are acceptable although azithromycin is most commonly prescribed''
''any of the following antibiotics are acceptable although azithromycin is most commonly prescribed''
*[[Azithromycin]] 500mg PO once daily for day #1 then 250mg PO once daily for days #2-5
*{{AntibioticDose|disease=Pertussis|drug=Azithromycin|dose=500mg PO once daily for day #1 then 250mg PO once daily for days #2-5|context=Adults}}
*[[Clarithromycin]] 500mg BID x7 days
*{{AntibioticDose|disease=Pertussis|drug=Clarithromycin|dose=500mg BID x7 days|context=Adults}}
*[[Erythromycin]] 500mg QID x7 days
*{{AntibioticDose|disease=Pertussis|drug=Erythromycin|dose=500mg QID x7 days|context=Adults}}

Revisión actual - 13:04 20 mar 2026

  • Antibiotics do not help with severity or duration but may decrease infectivity.
  • A reasonable guideline is to treat persons aged >1 year within 3 weeks of cough onset and infants aged <1 year and pregnant women (especially near term) within 6 weeks of cough onset. [1]
  • TMP--SMZ should not be administered to pregnant women, nursing mothers, or infants aged <2 months.[2]
  • The following regemins are for active disease or postexposure prophylaxis. If a patient is has confirmed disease and is likely to be in contact with infants or pregnant women then the patient should be treated as up to 6-8 weeks after the onset of their illness.

< 1 month old

Same antibiotics for active disease and postexposure prophylaxis

>1 month old

  • Azithromycin 10mg/kg (max 500mg/day) daily x 5 days
    • if > 6 months old then day 2-5 of treatment should be reduced to 5mg/kg (250mg/day max)
  • TMP/SMX 4mg/kg PO BID daily for 14 days (if > 2 months old)


Adults

any of the following antibiotics are acceptable although azithromycin is most commonly prescribed

  1. ↑ CDC - Pertussis http://www.cdc.gov/pertussis/clinical/treatment.html
  2. ↑ CDC MMWR Pertusis http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5414a1.htm
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