Diferencia entre revisiones de «Factor VIII inhibitor»
(Text replacement - "==References== " to "==References== <references/> ") |
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{{Increased bleeding DDX}} | {{Increased bleeding DDX}} | ||
== | ==Evaluation== | ||
*PTT does not correct after mixing | *PTT does not correct after mixing | ||
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==References== | ==References== | ||
<references/> | |||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revisión actual - 01:13 24 jul 2017
Background
Clinical Features
Differential Diagnosis
Coagulopathy
Platelet Related
- Too few
- Nonfunctional
Factor Related
- Acquired (Drug Related)
- Warfarin (Coumadin)
- Unfractionated heparin
- Low molecular weight heparin (i.e. enoxaparin (Lovenox), dalteparin)
- Factor Xa Inhibitors (e.g. rivaroxaban, apixaban, fondaparinux, edoxaban)
- Direct thrombin inhibitors (e.g. dabigatran, argatroban, bivalirudin)
- Illness induced
- Genetic
Evaluation
- PTT does not correct after mixing
Management
- Bleeding
- Give high dose Factor VII, prothrombin, or recombinant factor VIIa