Diferencia entre revisiones de «Template:Animal bite antibiotics»
(Convert to AntibioticDose with disease=Mammalian bites for SMW linking) |
(Add pediatric cat/dog bite and severe bite infection dosing) |
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====Cat and Dog Bites==== ''Coverage for [[Pasteurella|Pasteurella]], [[Strep|Strep]], and [[Staph|Staph]]'' | |||
====Cat and Dog Bites==== | |||
''Coverage for [[ | |||
*'''Consider for high-risk wounds''' | *'''Consider for high-risk wounds''' | ||
**wounds reaching the level of the muscle/tendon, wounds to the hand<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref>, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema | **wounds reaching the level of the muscle/tendon, wounds to the hand<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref>, violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema | ||
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====Human Bites==== | ====Human Bites==== All human bites should be strongly considered for antibiotic therapy.<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref> | ||
All human bites should be strongly considered for antibiotic therapy.<ref>[[EBQ:Antibiotic prophylaxis for mammalian bites|EBQ:Antibiotic prophylaxis for mammalian bites]]</ref> | |||
{{Human bite antibiotics}} | {{Human bite antibiotics}} | ||
====Mammalian Bites Severe Infections==== *{{AntibioticDose|disease=Mammalian bites|drug=Ampicillin/Sulbactam|dose=3g IV (50mg/kg) q6hrs|context=Severe mammalian bite infection|population=Adult}} OR | |||
====Mammalian Bites Severe Infections==== | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Ampicillin/Sulbactam|dose=3g IV (50mg/kg) q6hrs|context=Severe mammalian bite infection|population=Adult}} OR | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Cefoxitin|dose=1g IV q8hrs (25mg/kg q6hrs)|context=Severe mammalian bite infection|population=Adult}} OR | *{{AntibioticDose|disease=Mammalian bites|drug=Cefoxitin|dose=1g IV q8hrs (25mg/kg q6hrs)|context=Severe mammalian bite infection|population=Adult}} OR | ||
*{{AntibioticDose|disease=Mammalian bites|drug=Piperacillin/Tazobactam|dose=4.5g IV (80mg/kg) q8hrs|context=Severe mammalian bite infection|population=Adult}} OR | *{{AntibioticDose|disease=Mammalian bites|drug=Piperacillin/Tazobactam|dose=4.5g IV (80mg/kg) q8hrs|context=Severe mammalian bite infection|population=Adult}} OR | ||
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**{{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|dose=5mg/kg IV q12hrs|context=Severe mammalian bite with Clindamycin|display=TMP/SMX|population=Adult}} OR | **{{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|dose=5mg/kg IV q12hrs|context=Severe mammalian bite with Clindamycin|display=TMP/SMX|population=Adult}} OR | ||
**{{AntibioticDose|disease=Mammalian bites|drug=Ciprofloxacin|dose=400mg IV q12hrs|context=Severe mammalian bite with Clindamycin|population=Adult}} OR | **{{AntibioticDose|disease=Mammalian bites|drug=Ciprofloxacin|dose=400mg IV q12hrs|context=Severe mammalian bite with Clindamycin|population=Adult}} OR | ||
====Pediatric Cat and Dog Bites==== | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Amoxicillin/Clavulanate|dose=25-45mg/kg/day PO divided BID x 5-7 days|context=Pediatric cat and dog bites|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Clindamycin|dose=30mg/kg/day PO divided TID (max 1.8g/day)|context=Pediatric PCN allergy|population=Pediatric}} + {{AntibioticDose|disease=Mammalian bites|drug=Trimethoprim-Sulfamethoxazole DS|display=TMP/SMX|dose=8-12mg/kg/day (TMP) PO divided BID|context=Pediatric PCN allergy with Clindamycin|population=Pediatric}} | |||
====Pediatric Severe Bite Infections==== | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Ampicillin/Sulbactam|dose=50mg/kg IV q6hrs (max 3g/dose)|context=Pediatric Severe|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Piperacillin/Tazobactam|dose=80mg/kg IV q8hrs (max 4.5g)|context=Pediatric Severe|population=Pediatric}} '''OR''' | |||
*{{AntibioticDose|disease=Mammalian bites|drug=Ceftriaxone|dose=50mg/kg IV daily (max 2g)|context=Pediatric Severe|population=Pediatric}} + {{AntibioticDose|disease=Mammalian bites|drug=Metronidazole|dose=7.5mg/kg IV q8hrs (max 500mg)|context=Pediatric Severe with Ceftriaxone|population=Pediatric}} | |||
Revisión actual - 12:59 20 mar 2026
====Cat and Dog Bites==== Coverage for Pasteurella, Strep, and Staph
- Consider for high-risk wounds
- wounds reaching the level of the muscle/tendon, wounds to the hand[1], violation of bone or joint capsule, immunocompromised hosts, wounds associated with significant local edema
- Amoxicillin/Clavulanate 875mg PO BID x 5-7 days OR[2]
- Doxycycline 100mg PO BID x 14 days if penicillin allergic [3]
- Clindamycin 450mg (5mg/kg) PO q8hrs x 7 days PLUS
- Ciprofloxacin 500mg PO q12hrs x 7 days OR
- TMP/SMX 2 DS tabs (5mg/kg) PO q12hrs
====Human Bites==== All human bites should be strongly considered for antibiotic therapy.[4]
Requires polymicrobial coverage for: S. aureus, Strep Viridans, Bacteroides, Coagulase-neg Staph, Eikenella, Fusobacterium, Cornebacterium, peptostreptococus
- Amoxicillin/Clavulanate 875mg PO BID x 5-7 days OR
- Clindamycin 450mg (5mg/kg) PO q8hrs x 7 days PLUS
- Ciprofloxacin 500mg PO q12hrs x 7 days OR
- TMP/SMX 2 DS tabs (5mg/kg) PO q12hrs
Pediatric:
- Amoxicillin/Clavulanate 25-45mg/kg/day PO divided BID x 5-7 days OR
- Clindamycin 30mg/kg/day PO divided TID (max 1.8g/day) + TMP/SMX 8-12mg/kg/day (TMP) PO divided BID
====Mammalian Bites Severe Infections==== *Ampicillin/Sulbactam 3g IV (50mg/kg) q6hrs OR
- Cefoxitin 1g IV q8hrs (25mg/kg q6hrs) OR
- Piperacillin/Tazobactam 4.5g IV (80mg/kg) q8hrs OR
- Ceftriaxone 1g (50mg/kg) IV once + Metronidazole 500mg IV q8hrs OR
- Clindamycin 600mg IV q8hrs PLUS
- TMP/SMX 5mg/kg IV q12hrs OR
- Ciprofloxacin 400mg IV q12hrs OR
Pediatric Cat and Dog Bites
- Amoxicillin/Clavulanate 25-45mg/kg/day PO divided BID x 5-7 days OR
- Clindamycin 30mg/kg/day PO divided TID (max 1.8g/day) + TMP/SMX 8-12mg/kg/day (TMP) PO divided BID
Pediatric Severe Bite Infections
- Ampicillin/Sulbactam 50mg/kg IV q6hrs (max 3g/dose) OR
- Piperacillin/Tazobactam 80mg/kg IV q8hrs (max 4.5g) OR
- Ceftriaxone 50mg/kg IV daily (max 2g) + Metronidazole 7.5mg/kg IV q8hrs (max 500mg)
- ↑ EBQ:Antibiotic prophylaxis for mammalian bites
- ↑ Griego RD, Rosen T, Orengo IF, Wolf JE. Dog, cat, and human bites: a review. J Am Acad Dermatol. 1995;33:1019–29.
- ↑ Talan DA, Citron DM, Abrahamian FM, Moran GJ, Goldstein EJ. Bacteriologic analysis of infected dog and cat bites. Emergency Medicine Animal Bite Infection Study Group. N Engl J Med. 1999;340:85–92.
- ↑ EBQ:Antibiotic prophylaxis for mammalian bites