Diferencia entre revisiones de «Hydralazine»
(Created page with "==General== *Type: *Dosage Forms: *Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== *Pregnancy Rating: *Lac...") |
(Switch SMW query from broadtable to table format for better layout with TOC) |
||
| (No se muestran 19 ediciones intermedias de 8 usuarios) | |||
| Línea 1: | Línea 1: | ||
==General== | ==General== | ||
*Type: | *Type: Vasodilator | ||
*Dosage Forms: | *Dosage Forms: 10, 25, 50, 100; PO, IM, IV | ||
*Common Trade Names: | *Common Trade Names: Apresoline | ||
==Adult Dosing== | ==Adult Dosing== | ||
*hypertension: 10 - 50mg PO QID | |||
*Hypertensive crisis: 10-20mg IM/IV q2-4h | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Hypertensive Crisis: | |||
#1 mo - 12 years: 0.1 - 0.5mg/kg IM/IV q4-6h, max dose of 20mg | |||
#> 12 years old: 10 - 20mg IV q2-4h | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: | *Lactation: Probably Safe | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: CrCl 10-50: give q8h, CrCl <10, give q8-16h | ||
**Pediatric | **Pediatric: CrCl 10-50: give q8h, CrCl <10, give q8-16h | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: not defined | ||
**Pediatric | **Pediatric: not defined | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
*mitral valvular rheumatic heart disease | |||
*Caution if renal impairment | |||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*MI | |||
*neutropenia | |||
*lupus erythematosus (SLE) | |||
*peripheral neuritis | |||
===Common=== | ===Common=== | ||
*headache | |||
*tachycardia | |||
*angina | |||
*nausea/vomiting | |||
*rash | |||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 3-7 hours | ||
*Metabolism: | *Metabolism: liver | ||
*Excretion: | *Excretion: urine, feces | ||
*Mechanism of Action: | *Mechanism of Action: directly dilates peripheral vessels | ||
==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Hydralazine]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=table | |||
|headers=plain | |||
|mainlabel=- | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
==See Also== | ==See Also== | ||
==References== | |||
<references/> | <references/> | ||
[[Category: | |||
[[Category:Pharmacology]] | |||
[[Category:Cardiology]] | |||
Revisión actual - 21:57 20 mar 2026
General
- Type: Vasodilator
- Dosage Forms: 10, 25, 50, 100; PO, IM, IV
- Common Trade Names: Apresoline
Adult Dosing
- hypertension: 10 - 50mg PO QID
- Hypertensive crisis: 10-20mg IM/IV q2-4h
Pediatric Dosing
- Hypertensive Crisis:
- 1 mo - 12 years: 0.1 - 0.5mg/kg IM/IV q4-6h, max dose of 20mg
- > 12 years old: 10 - 20mg IV q2-4h
Special Populations
- Pregnancy Rating: C
- Lactation: Probably Safe
- Renal Dosing
- Adult: CrCl 10-50: give q8h, CrCl <10, give q8-16h
- Pediatric: CrCl 10-50: give q8h, CrCl <10, give q8-16h
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- mitral valvular rheumatic heart disease
- Caution if renal impairment
Adverse Reactions
Serious
- MI
- neutropenia
- lupus erythematosus (SLE)
- peripheral neuritis
Common
- headache
- tachycardia
- angina
- nausea/vomiting
- rash
Pharmacology
- Half-life: 3-7 hours
- Metabolism: liver
- Excretion: urine, feces
- Mechanism of Action: directly dilates peripheral vessels
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Hypertensive emergency | 5-20 mg IV q4-6 hr | Antihypertensive | IV | Adult |
| Stroke (main) | 10-20 mg IV, repeat q4-6h | BP control in acute stroke | IV | Adult |