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CDC 2009
==Background==
===High-risk groups===
*Pregnant- increased rates of SAB, preterm labor
*Chronic lung disease
*Immunosuppressed
*Cardiac
*[[Diabetes mellitus]]


-March/April 2009, an outbreak of H1N1 influenza A virus infection was first detected in Mexico.
===Screening===
*Individuals with an acute febrile respiratory illness (a measured temperature of 100ºF or higher and recent onset of at least one of the following: rhinorrhea, nasal congestion, sore throat, or cough) or sepsis-like syndrome.
*HIGH PRIORITY for hospitalized patients and those at high-risk for severe disease.


-June 11, 2009, WHO raised its pandemic alert level to the highest level, phase 6, indicating widespread community transmission on at least two continents.
==Clinical Features==




Age distribution:
==Differential Diagnosis==


Oddly infection occurs disproportionately in individuals who are not at the extremes of age.


Distrubtion ages 5 and 24-years-old.
==Evaluation==
*Rapid Flu nasal swab 60-80% sensitive in detecting influenza A
**If patient is negative, severely ill and will be hospitalized, send viral culture
*PCR is the recommended confirmatory test


Few cases and no deaths reported in people older than 64 years old (? previous immunity)
==Management==
*Adult: [[Tamiflu]] 75-mg capsule twice per day for 5 days
**All hospitalized patients with confirmed, probable or suspected novel influenza (H1N1)
**Patients who are at higher risk for seasonal influenza complications


''Most effective when started within 48 hours of illness onset.''


High-risk groups:
===Post-exposure chemoprophylaxis===
*[[Tamiflu]] 75mg PO daily x 10 days (10 days after the last known exposure to novel (H1N1) influenza)


Pregnant- incr rates of SAB, preterm labor
''If the contact occurred with a patient after 7 days of symptom onset, then chemoprophylaxis is not necessary. This is the presumed post-infectious period.''


Chronic lung disease
==Disposition==
 
Immunosuppressed
 
Cardiac
 
DM
 
 
Screening:
 
Individuals with an acute febrile respiratory illness (a measured temperature of 100ºF or higher and recent onset of at least one of the following: rhinorrhea, nasal congestion, sore throat, or cough) or sepsis-like syndrome- HIGH PRIORITY for hospitalized patients and those at high-risk for severe disease.
 
 
Tests:
 
Rapid Flu nasal swab 60-80% sensitive in detecting influenza A
 
If patient is negative, severely ill and will be hospitalized, send viral culture
 
PCR is the recommended confirmatory test
 
 
Treatment:
 
* All hospitalized patients with confirmed, probable or suspected novel influenza (H1N1).
* Patients who are at higher risk for seasonal influenza complications
Most effective when started within 48 hours of illness onset.
 
Adult: 75-mg capsule twice per day for 5 days
 
 
Post-exposure antiviral chemoprophylaxis is recommended for those with close contacts:
 
Tamiflu 75mg po daily x 10 days (10 days after the last known exposure to novel (H1N1) influenza.)
 
If the contact occurred with a patient after 7 days of symtpom onset, then chemoprophylaxis is not necessary. This is the presumed post-infectious period.




==See Also==
*[[Influenza]]


==References==
<references/>


[[Category:ID]]
[[Category:ID]]

Revisión actual - 00:11 26 feb 2017

Background

High-risk groups

  • Pregnant- increased rates of SAB, preterm labor
  • Chronic lung disease
  • Immunosuppressed
  • Cardiac
  • Diabetes mellitus

Screening

  • Individuals with an acute febrile respiratory illness (a measured temperature of 100ºF or higher and recent onset of at least one of the following: rhinorrhea, nasal congestion, sore throat, or cough) or sepsis-like syndrome.
  • HIGH PRIORITY for hospitalized patients and those at high-risk for severe disease.

Clinical Features

Differential Diagnosis

Evaluation

  • Rapid Flu nasal swab 60-80% sensitive in detecting influenza A
    • If patient is negative, severely ill and will be hospitalized, send viral culture
  • PCR is the recommended confirmatory test

Management

  • Adult: Tamiflu 75-mg capsule twice per day for 5 days
    • All hospitalized patients with confirmed, probable or suspected novel influenza (H1N1)
    • Patients who are at higher risk for seasonal influenza complications

Most effective when started within 48 hours of illness onset.

Post-exposure chemoprophylaxis

  • Tamiflu 75mg PO daily x 10 days (10 days after the last known exposure to novel (H1N1) influenza)

If the contact occurred with a patient after 7 days of symptom onset, then chemoprophylaxis is not necessary. This is the presumed post-infectious period.

Disposition

See Also

References