Diferencia entre revisiones de «Misoprostol»
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==Comments== | ==Comments== | ||
==Indications by Condition== | |||
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==See Also== | ==See Also== | ||
Revisión actual - 21:57 20 mar 2026
General
- Type: Prostaglandin
- Dosage Forms:
- Routes of Administration:
- Common Trade Names: Cytotec
Adult Dosing
Postpartum hemorrhage
- Second Line therapy and can be administered sublingually, orally, vaginally, and rectally.[1]
- 1,000 mcg administered rectally
- 800 mcg PO
Pediatric Dosing
Special Populations
- Pregnancy Rating: X
- Lactation risk: Excreted in breastmilk
- Renal Dosing: not defined
- Hepatic Dosing: not defined
Contraindications
- Allergy to class/drug
- Pregnancy (when used to treat ulcers)
Adverse Reactions
Serious
- Anaphylaxis
- Dysrhythmia, MI
- GI bleed
- Uterine rupture
- Thromboembolic disorder
Common
- Diarrhea, abdominal pain, flatulence, nausea
- Headache
- Anemia
- Chest pain
Pharmacology
- Half-life: 20-40min
- Metabolism: Hepatic
- Excretion:
- Mechanism of Action: Synthetic prostaglandin E analogue
Comments
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| First trimester abortion | 800mcg vaginally, repeat once in 7 days if no response | Medical management of early pregnancy loss (<12 weeks) | Vaginal | Adult |
| Postpartum hemorrhage | 600 mcg SL or 1000 mcg PR | 2nd line uterotonic | SL/PR | Adult |
See Also
References
- ↑ Mousa HA, Alfirevic Z. Treatment for primary postpartum haemorrhage. Cochrane Database Syst Rev. 2003;(1):CD003249.