Diferencia entre revisiones de «Chagas disease»
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==Background== | ==Background== | ||
*Also known as American Trypanosomiasis | *Also known as American Trypanosomiasis<ref>Bern C. Chagas Disease. N Engl J Med. 2015;373(5):456-466. PMID 26222561</ref> | ||
*Endemic in rural parts of Cental and South America | *Endemic in rural parts of Cental and South America | ||
**Rare cases found in Southern United States | **Rare cases found in Southern United States | ||
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===Transmission=== | ===Transmission=== | ||
[[File: Triatoma.jpg|thumb|''Triatoma infestans,''a common vector for ''T. cruzi'']] | |||
*Disease of poverty | *Disease of poverty | ||
**Spread by the [[wikipedia:Triatominae|Triatominae]] bug (also known as the kissing bug) | **Spread by the [[wikipedia:Triatominae|Triatominae]] bug (also known as the kissing bug) | ||
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*Between 20-40% of patients will develop chronic complications | *Between 20-40% of patients will develop chronic complications | ||
*'''Cardiac complications''' | *'''Cardiac complications''' | ||
**Dilated cardiomyopathy ([[CHF]]) | **[[Dilated cardiomyopathy]] ([[CHF]]) | ||
**[[Dysrhythmias]] | **[[Dysrhythmias]] | ||
*'''GI complications''' | *'''GI complications''' | ||
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**[[Achalasia]] | **[[Achalasia]] | ||
**[[Volvulus]] | **[[Volvulus]] | ||
**[[Hepatosplenomegaly]] (secondary to HF) | **[[Hepatomegaly|Hepatosplenomegaly]] (secondary to HF) | ||
*'''Neuro symptoms''' | *'''Neuro symptoms''' | ||
**Neuritis | **Neuritis | ||
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*[[Parasitic Diseases]] | *[[Parasitic Diseases]] | ||
*[[Travel Medicine]] | *[[Travel Medicine]] | ||
*[[Cardiomyopathy]] | |||
==References== | ==References== | ||
Revisión actual - 10:17 22 mar 2026
Background
- Also known as American Trypanosomiasis[1]
- Endemic in rural parts of Cental and South America
- Rare cases found in Southern United States
- Caused by the parasite trypanosoma cruzi
- Vector: Reduviid (kissing bug)
- The parasite is transmitted in the feces of the host vector
- When the vector bites, it also defecates and the parasites enter the blood stream through the bite wound
Transmission
- Disease of poverty
- Spread by the Triatominae bug (also known as the kissing bug)
- The Triatomina bug thrives in housing that is old, has thatched roofs and dwellings where the roof does not abut the wall.
- Spread by the Triatominae bug (also known as the kissing bug)
- Other methods of transmission
- Vertical (mother to child)
- Transfusion/organ donation
Clinical Features
Acute phase
- Romañas sign
- swelling of the eye thought to be secondary to rubbing the feces into the eye
- Chagoma
- Localized swelling at the area of parasite entry
- Non-specific signs and symptoms
- Serious complications
Chronic phase
- Between 20-40% of patients will develop chronic complications
- Cardiac complications
- GI complications
- Megaesophagus
- Megacolon
- Achalasia
- Volvulus
- Hepatosplenomegaly (secondary to HF)
- Neuro symptoms
- Neuritis
Differential Diagnosis
Evaluation
Management
- Benznidazole or Nifurtimox
- Symptomatic treatment
External Links
See Also
References
- ↑ Bern C. Chagas Disease. N Engl J Med. 2015;373(5):456-466. PMID 26222561