Diferencia entre revisiones de «Tramadol»
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==General== | ==General== | ||
*Type: Opioid | *Type: [[Opioid]] | ||
*Dosage Forms: PO, IM, IV, PR | *Dosage Forms: PO, IM, IV, PR; immediate and extended release formulations; combination formulations with acetaminophen (Tramacet) | ||
*Common Trade Names: Ultram, Ryzolt, Zytram | *Common Trade Names: Ultram, Ryzolt, Zytram | ||
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*Respiratory Depression | *Respiratory Depression | ||
*Suicidal ideation | *Suicidal ideation | ||
*Seizures | *[[Seizures]] | ||
*Anaphylaxis | *[[Anaphylaxis]] | ||
*Serotonin syndrome | *[[Serotonin syndrome]] | ||
*[[Stevens-Johnson syndrome]] | *[[Stevens-Johnson syndrome]] | ||
===Common=== | ===Common=== | ||
*Nausea | *[[Nausea]] | ||
*Rash | *[[Rash]] | ||
*Headache | *Headache | ||
*Fatigue | *Fatigue | ||
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*Excretion: urine | *Excretion: urine | ||
*Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | *Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | ||
==See Also== | |||
*[[Opioids]] | |||
*[[Acute pain management]] | |||
*[[Serotonin syndrome]] | |||
*[[Seizure]] | |||
==References== | |||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Tramadol]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=table | |||
|headers=plain | |||
|mainlabel=- | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
Revisión actual - 09:15 22 mar 2026
General
- Type: Opioid
- Dosage Forms: PO, IM, IV, PR; immediate and extended release formulations; combination formulations with acetaminophen (Tramacet)
- Common Trade Names: Ultram, Ryzolt, Zytram
Adult Dosing
General
- Moderate to severe pain:
- 50-100mg PO q4-6h PRN
- Chronic severe pain:
- 100-300mg ER PO daily
Pediatric Dosing
- Not Currently recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: Probably safe
- Renal Dosing
- Adult: CrCL < 30: given q12h, max 200mg/day
- Pediatric: none
- Hepatic Dosing
- Adult: cirrhosis: 50mg q12h, max 100mg/day
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- Asthma, acute
- Respiratory depression
- Severe hepatic impairment
- Severe renal impairment
- Acute alcohol intoxication
Adverse Reactions
Serious
- Respiratory Depression
- Suicidal ideation
- Seizures
- Anaphylaxis
- Serotonin syndrome
- Stevens-Johnson syndrome
Common
Pharmacology
- Half-life: 6.3 - 7.9 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake
See Also
References
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Acute pain management | 50-100 mg PO q4-6h | Step 2 - Moderate pain (mild opioid) | PO | Adult |