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==Types==
==Types==
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| colspan="5" | INTERMEDIATE ACTING
| colspan="5" | '''INTERMEDIATE ACTING'''
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[[File:Insulin.jpg|thumbnail]]
{{Common Anti-hyperglycemic Drugs and Pharmacology}}


==Insulin Sliding Scale==
==Insulin Sliding Scale==
*Dosing depends on the patient's level of insulin resistance. The high dose regimen should be reserved for the severely insulin resistant patients.
*Dosing depends on the patient's level of insulin resistance.  
*The example sliding scales are for regular insulin with blood glucose (BG) measured in mg/dL
*The example sliding scales are for regular insulin with blood glucose (BG) measured in mg/dL
*Patients with renal insufficiency will excrete insulin at a lower rate and should be started on a lower dosing regimen.


===Low Dose ===
===Low Dose (Renal Insufficiency)===
*BG 150-199: 1 unit bolus Insulin  
*BG 150-199: 1 unit bolus Insulin  
*BG 200-249: 2 units bolus Insulin
*BG 200-249: 2 units bolus Insulin
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*BG Over 350: 5 units bolus Insulin
*BG Over 350: 5 units bolus Insulin


===Medium Dose===
===Medium Dose (Standard)===
*BG 150-199: 1 unit bolus Insulin  
*BG 150-199: 1 unit bolus Insulin  
*BG 200-249: 3 units bolus Insulin
*BG 200-249: 3 units bolus Insulin
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*BG Over 350: 8 units bolus Insulin
*BG Over 350: 8 units bolus Insulin


===High Dose===
===High Dose (Severely Insulin Resistant)===
*BG 150-199: 2 unit bolus Insulin
*BG 150-199: 2 unit bolus Insulin
*BG 200-249: 4 units bolus Insulin
*BG 200-249: 4 units bolus Insulin
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*BG 300-349: 10 units bolus Insulin
*BG 300-349: 10 units bolus Insulin
*BG Over 350: 12 units bolus Insulin
*BG Over 350: 12 units bolus Insulin
==Indications by Condition==
''The following table is automatically generated from disease/condition pages across WikEM.''
{{#ask:[[Has DrugName::Insulin]]
|?Has Indication=Indication
|?Has Dose=Dose
|?Has Context=Context
|?Has Route=Route
|?Has Population=Population
|format=table
|headers=plain
|mainlabel=-
|sort=Has Indication
|limit=50
}}


==See Also==
==See Also==
*[[Diabetes (Main)]]
*[[Diabetes (Main)]]


[[Category:Drugs]]
==References==
[[Category:Endo]]
<references/>
 
[[Category:Pharmacology]]
[[Category:Endocrinology]]

Revisión actual - 09:11 22 mar 2026

Types

Type Onset of action (h) Peak action Effective duration Max duration
RAPID ACTING

Lispro

(humalog)

0.25-0.5
 0.5-1.25 3-4 4-6

Aspart

(novolog)

0.25-0.5
 0.5-1.25 3-4 4-6

Glulisine

(apidra)

0.25-0.5 0.25-1.25
 3-4 4-6
SHORT ACTING
Regular 0.5-1 2-3 3-6 6-8
INTERMEDIATE ACTING
NPH 2-4 6-10 10-16 14-18
LONG ACTING

glargine

(Lantus)

3-4 8-16 18-20 20-24

detemir

(Levemir)

3-4 6-8 14 ~20
Insulin.jpg

Common Anti-hyperglycemic Drugs and Pharmacology

Drug Pharmacology
Onset Peak Duration
Rapid-acting insulin

  • Aspart (Novolog)
  • Lispro (Humalog)
 15-30min 1-2h 3-5h
Short-acting insulin

  • Regular
 30-60min 2-4h 6-10h
Intermediate-acting insulin

  • NPH (Humulin, Novolin)
 1-3h 4-12h 18-24h
Long-acting insulin

  • Glargine (Lantus)
 2-4h None 24h
Sulfonylurea

  • Glimepiride
  • Glipizide (Glucotrol)
  • Glyburide (Glycron, Micronase)
 – 2-6h 12-24h

See also GLP-1 agonists

Insulin Sliding Scale

  • Dosing depends on the patient's level of insulin resistance.
  • The example sliding scales are for regular insulin with blood glucose (BG) measured in mg/dL

Low Dose (Renal Insufficiency)

  • BG 150-199: 1 unit bolus Insulin
  • BG 200-249: 2 units bolus Insulin
  • BG 250-299: 3 units bolus Insulin
  • BG 300-349: 4 units bolus Insulin
  • BG Over 350: 5 units bolus Insulin

Medium Dose (Standard)

  • BG 150-199: 1 unit bolus Insulin
  • BG 200-249: 3 units bolus Insulin
  • BG 250-299: 5 units bolus Insulin
  • BG 300-349: 7 units bolus Insulin
  • BG Over 350: 8 units bolus Insulin

High Dose (Severely Insulin Resistant)

  • BG 150-199: 2 unit bolus Insulin
  • BG 200-249: 4 units bolus Insulin
  • BG 250-299: 7 units bolus Insulin
  • BG 300-349: 10 units bolus Insulin
  • BG Over 350: 12 units bolus Insulin


Indications by Condition

The following table is automatically generated from disease/condition pages across WikEM.

IndicationDoseContextRoutePopulation
Beta-blocker toxicity1 unit/kg IV bolus with D50, then 0.5-1 unit/kg/hr dripHigh-dose insulin euglycemic therapyIV/IV dripAdult
Calcium channel blocker toxicity1 unit/kg IV bolus with D50, then 0.5-1 unit/kg/hr drip (max 2 units/kg/hr)High-dose insulin euglycemic therapy (best evidence)IV/IV dripAdult
Diabetic ketoacidosis0.1 units/kg/hr IV infusion (no bolus); reduce to 0.02-0.05 units/kg/hr when BG <250IV insulin for moderate-severe DKAIV dripAdult
Diabetic ketoacidosis0.3 units/kg SC initial, then 0.1-0.2 units/kg SC q1-2hSC insulin for mild DKA onlySCAdult
Diabetic ketoacidosis (peds)0.1 units/kg/hr IV dripDKA managementIV dripPediatric

See Also

References

Obtenido de «https://www.wikem.org/w/index.php?title=Insulin&oldid=388989»