Diferencia entre revisiones de «Doxylamine»
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==Administration== | ==Administration== | ||
*Type:[[ Antihistamine]] | *Type: [[Antihistamine]] | ||
*Dosage Forms: | *Dosage Forms: | ||
*Routes of Administration: oral | *Routes of Administration: oral | ||
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*Rhinitis: 7.5-12.5mg PO q4-6h | *Rhinitis: 7.5-12.5mg PO q4-6h | ||
*[[Insomnia]]: 25-50mg PO | *[[Insomnia]]: 25-50mg PO | ||
*[[Nausea in pregnancy]]/[[hyperemesis gravidarum]]: 12.5mg q6-8hrs | *[[Nausea in pregnancy]]/[[hyperemesis gravidarum]]: 12.5mg q6-8hrs (often used in combination with [[pyridoxine]]) | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
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==Comments== | ==Comments== | ||
==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Doxylamine]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=table | |||
|headers=plain | |||
|mainlabel=- | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
==See Also== | ==See Also== | ||
Revisión actual - 21:57 20 mar 2026
Administration
- Type: Antihistamine
- Dosage Forms:
- Routes of Administration: oral
- Common Trade Names: Unisom
Adult Dosing
- Rhinitis: 7.5-12.5mg PO q4-6h
- Insomnia: 25-50mg PO
- Nausea in pregnancy/hyperemesis gravidarum: 12.5mg q6-8hrs (often used in combination with pyridoxine)
Pediatric Dosing
Not recommended for children <12 yo due to tendency to paradoxical reactions
- 2-6yo: 1.9 to 3.125 mg q4-6h
- 6-12 yo: 3.75 to 6.25 mg q4-6h
Special Populations
- Pregnancy Rating: A
- Lactation risk: Infant risk cannot be ruled out
- Renal dosing: no adjustment
- Hepatic dosing: no adjustment
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
- Somnolence
Pharmacology
- Half-life: 10-18h
- Metabolism: Hepatic - CYP450
- Excretion: Urine
Mechanism of Action
- H1-histamine blocker
Comments
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Hyperemesis gravidarum | 12.5 mg q6-8hr | 1st line antiemetic (add to B6) | PO | Adult |