Diferencia entre revisiones de «Permethrin»
Sin resumen de edición |
(Restore original dosing content alongside dynamic SMW tables) |
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| (No se muestran 2 ediciones intermedias de 2 usuarios) | |||
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*Body/pubic lice: Apply 1% cream rinse to affected areas, then wash off after 10 minutes | *Body/pubic lice: Apply 1% cream rinse to affected areas, then wash off after 10 minutes | ||
*Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | *Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Permethrin]] [[Has Population::Adult]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | *Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment | ||
*Scabies, >2mo: Apply cream head to toe,wash with soap/water after 8-14h. Repeat application if living mites present 14 days after initial treatment | *Scabies, >2mo: Apply cream head to toe,wash with soap/water after 8-14h. Repeat application if living mites present 14 days after initial treatment | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Permethrin]] [[Has Population::Pediatric]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Special Populations== | ==Special Populations== | ||
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<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:ID]] | |||
Revisión actual - 02:39 20 mar 2026
Administration
- Type: Pediculicide
- Dosage Forms: Cream or lotion
- Routes of Administration: Topical
- Common Trade Names: Nix, Elimite
Adult Dosing
- Scabies: apply 5% cream head to toe, leave on 8-14 hrs prior to washing with soap/water. Repeat application in 14 days if living mites still present
- Body/pubic lice: Apply 1% cream rinse to affected areas, then wash off after 10 minutes
- Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Scabies | 5% cream neck down leave 8-12hrs repeat 1-2wks | First line adults |
Pediatric Dosing
- Head lice: Apply to damp, recently shampooed (but not conditioned!) hair. Saturate hair and scalp; leave on for 10min then rinse. Remove nits with nit comb. Repeat if live lice present 7 days after initial treatment
- Scabies, >2mo: Apply cream head to toe,wash with soap/water after 8-14h. Repeat application if living mites present 14 days after initial treatment
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Scabies | 5% cream, apply head to toe (avoid mucous membranes), leave 8-12hrs, wash off; repeat in 1-2 weeks | Pediatric (>2 months) |
Special Populations
- Pregnancy Rating: B
- Lactation risk: Infant risk minimal
- Renal dosing: not defined
- Hepatic dosing: not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Serious reactions are rare
Common
- Rash, erythema, pruritus, burning/stinging sensation
- Swelling
Pharmacology
- Topical: <2% absorbed
- Half-life:
- Metabolism:
- Excretion: Renal
Mechanism of Action
- Disrupts neuronal sodium channel current in louse/mite, leading to delayed repolarization of nerve and subsequent paralysis/death