Diferencia entre revisiones de «INH toxicity»

Revisión actual - 14:56 8 feb 2021

Redirect to:

Authors:

@@ Línea 1: / Línea 1: @@
-==Background==
+#REDIRECT[[Isoniazid toxicity]]
-*Causes low Pyridoxine B6 stores
-*B6 used to make gaba- an inhibitory neurotransmitter
-*Also inhibits lactate to pyruvate conversion
-==Treatment==
-*Adults - 1 g of pyridoxine for each gram of INH ingested, to a maximum of 5 g
-*Children - 70 mg/kg
-Rate - slow IV infusion at approximately 0.5 g/min until the seizures stop or the maximum dose is reached. Remainder of dose infused over 4 to 6 hours.
-==Source==
-/06 MISTRY & Goldfrank's Toxicologic Emergencies
-[[Category:Tox]]