Diferencia entre revisiones de «Inhalant abuse»
(Text replacement - "Category:Tox" to "Category:Toxicology") |
Sin resumen de edición |
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==Management== | ==Management== | ||
*Supportive care | *Supportive care, cardioversion for dysrhythmias | ||
**Careful use of vasopressors as sympathomimetics may increase risk of dysrhythmias | |||
*If founded down with sudden death with history of recent inhalant abuse → give beta-blocker (propanolol, esmolol) | *If founded down with sudden death with history of recent inhalant abuse → give beta-blocker (propanolol, esmolol) | ||
**Thought to counteract myocardial sensitization | **Thought to counteract myocardial sensitization | ||
Revisión del 14:34 22 jun 2016
Background
- First described in the 1950s
- Most common abusant in preteens 11-13yo
- Most abused: gasoline, solvents like toluene, spray paints, lighter fluid, air fresheners, glue, and electronic cleaners (halogenated hydrocarbons)
- Includes: "sniffing", "huffing", "bagging", and "dusting"
Clinical Features
- General: Euphoria, hallucinations
- Neuro: Impaired motor activity, ataxia, depressed mentation, withdrawal potential
- Cardiac: Widened QRS, prolonged QT, syncope, arrhythmias
- Skin: May cause dermal burns
- "Sudden sniffing death" - thought to be occur with sudden catecholamine surge on a "sensitized" myocardium
Differential Diagnosis
Drugs of abuse
- 25C-NBOMe
- Alcohol
- Amphetamines
- Bath salts
- Cocaine
- Difluoroethane
- Ecstasy
- Gamma hydroxybutyrate (GHB)
- Heroin
- Inhalant abuse
- Hydrocarbon toxicity
- Difluoroethane (electronics duster)
- Marijuana
- Kratom
- Phencyclidine (PCP)
- Psilocybin ("magic mushrooms")
- Synthetic cannabinoids
- Chloral hydrate
- Body packing
Diagnosis
- Generally a clinical diagnosis.
Management
- Supportive care, cardioversion for dysrhythmias
- Careful use of vasopressors as sympathomimetics may increase risk of dysrhythmias
- If founded down with sudden death with history of recent inhalant abuse → give beta-blocker (propanolol, esmolol)
- Thought to counteract myocardial sensitization
Disposition
- Based on patient's clinical status.