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==Background==
==Background==
The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus).  Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed.  The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.
The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus).  Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to [[Ethanol|ethanol]]. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed.  The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.


==Medications with Similar Effects==
==Medications with Similar Effects==
* Antibiotics ([[Metronidazole|metronidazole]], cephalosporins (cefotetan)
* Antibiotics ([[Metronidazole|metronidazole]], [[Cephalosporins|cephalosporins]] (cefotetan))
* Antifungals ([[Griseofulvin]])
* Antifungals ([[Griseofulvin]])


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Care is primarily supportive.
Care is primarily supportive.


[[Categories:Drugs]]
[[Category:Drugs]]

Revisión del 06:02 6 ago 2015

Background

The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus). Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed. The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.

Medications with Similar Effects

Treatment

Care is primarily supportive.