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== Acute Pelvic Pain Differential Diagnosis ==
{{AdultPage|Prepubertal pelvic pain}}
==== Gynecologic/Obstetric ====
==Background==
*Pregnancy-related
*This page outlines the general approach to pelvic pain in the emergency department
**[[Ectopic Pregnancy]]
*Pelvic pain is a common ED complaint, particularly in women of reproductive age
**Abortion, threatened or incomplete
*Must always consider pregnancy-related emergencies ([[ectopic pregnancy]], [[miscarriage]]) as potential life-threatening etiologies
**Septic Abortion
*Other emergent causes include [[ovarian torsion]], [[testicular torsion]], and [[ruptured ovarian cyst]] with hemorrhage
*Acute Infections
{{Abdominal pain location}}
**Endometritis
[[File:Blausen 0732 PID-Sites.png|thumb|Pelvic anatomy.]]
**[[Pelvic Inflammatory Disease (PID)]]
**[[TOA]]
*Adnexal Disorders
**Hemorrhage/rupture of ovarian cyst
**Torsion of Adnexa
**Twisted paraovarian cyst
*Recurrent
**Mittelschmerz (midcycle pain)
**Primary/Secondary Dysmenorrhea
**Endometriosis
*[[Vulvovaginitis]]
**[[Bacterial Vaginosis]]
**[[Candida Vaginitis]]
**[[Trichomonas]]
**[[Contact Vulvovaginitis]]
**Atrophic vaginitis


==== Genitourinary ====  
==Clinical Features==
*[[Cystitis]]
===Red Flags===
*[[Pyelonephritis]]
*Hemodynamic instability (consider ruptured [[ectopic pregnancy]], hemorrhagic cyst, ruptured AAA)
*Ureteral lithiasis
*Peritoneal signs (rebound, guarding, rigidity)
*Fever with pelvic pain (consider [[tubo-ovarian abscess]], [[pelvic inflammatory disease|PID]], or other pelvic abscess)
*Positive pregnancy test with pain (ectopic until proven otherwise)
*Acute onset severe unilateral pain (consider [[ovarian torsion]] or [[testicular torsion]])


==== Gastrointestinal ====
===History===
*Gastroenteritis
*Onset, duration, character, location, radiation, severity
*[[Appendicitis]]
*Menstrual history: LMP, regularity, abnormal bleeding
*Bowel obstruction
*Sexual history: activity, contraception, STI risk factors
*Perirectal abscess
*Obstetric history: prior pregnancies, ectopics
*[[Diverticulitis]]
*Associated symptoms: vaginal bleeding/discharge, urinary symptoms, GI symptoms, fever
*Inflammatory bowel disease
*Surgical history: prior pelvic/abdominal surgeries
*[[Irritable Bowel Syndrome (IBS)]]


==== Musculoskeletal ====
===Physical Exam===
*Abdominal wall hematoma
*Abdominal exam: tenderness, distension, peritoneal signs
*Psoas hematoma
*Pelvic exam: cervical motion tenderness, adnexal tenderness/masses, vaginal discharge/bleeding
*[[Hernia]]
*Consider rectal exam if indicated
*Testicular exam in males with lower pelvic/groin complaints


==== Vascular ====  
==Differential Diagnosis==
*Pelvic thrombophlebitis
{{Pelvic pain DDX}}
*[[Abdominal Aortic Aneurysm (AAA)]]
{{Postmenopausal Pelvic Pain DDX}}
*Ischemic bowel ([[Mesenteric Ischemia]])


== Postmenopausal Pelvic Pain DDX ==
==Evaluation==
==== Gynecologic ====
===Immediate===
*[[Vulvovaginitis]]
*Urine pregnancy test (mandatory in all women of reproductive age)
**Atrophic
*Point-of-care ultrasound ([[POCUS]]) if hemodynamically unstable or concern for ectopic, free fluid, or torsion
**Infectious
**Allergic
*Uterine prolapse
*Cervical polyps
*Uterine fibroids
*Endometrial hyperplasia
*Neoplasm
**Uterine
**Ovarian


==== Gastrointestinal ====
===Laboratory===
*Rectocele
*[[CBC]], [[BMP]]
*[[Diverticulitis]]
*[[Urinalysis]], urine culture
*Neoplasm
*Quantitative beta-hCG if pregnancy test positive
*[[Appendicitis]]
*Gonorrhea/chlamydia testing (NAAT) if concern for [[PID]] or STI
*Ischemic Bowel ([[Mesenteric Ischemia]])
*[[ESR]]/[[CRP]] if concern for inflammatory process
==== Urologic ====
*Type and screen if significant bleeding or concern for ectopic
*Infection
**[[Cystitis]]
**[[Urethritis]]
**[[Pyelonephritis]]
*Cystourethrocele


== See Also ==
===Imaging===
*[[Prepubertal Pelvic Pain]]
*Transvaginal ultrasound is the primary imaging modality for pelvic pain
**Evaluate for intrauterine pregnancy, ectopic pregnancy, ovarian cyst/torsion, free fluid
*[[CT abdomen pelvis]] if broad differential or concern for appendicitis, diverticulitis, or abscess
*Consider [[MRI]] for suspected ovarian torsion with nondiagnostic ultrasound (especially in pregnancy)
 
==Management==
===General===
*IV access, fluid resuscitation if hemodynamically unstable
*Analgesia: [[ketorolac]] (if not pregnant), [[acetaminophen]], opioids for severe pain
*Antiemetics as needed
 
===Condition-Specific===
*[[Ectopic pregnancy]]: emergent OB/GYN consultation, may require surgical intervention or methotrexate
*[[Ovarian torsion]]: emergent GYN consultation for surgical detorsion
*[[Ruptured ovarian cyst]]: pain control, hemodynamic monitoring; GYN consult if hemorrhagic
*[[Pelvic inflammatory disease]]: antibiotics per CDC guidelines (see [[PID]] page)
*[[Tubo-ovarian abscess]]: IV antibiotics, GYN consultation, possible drainage
*[[Endometriosis]]: NSAIDs, hormonal management, GYN follow-up
*[[Kidney stones|Nephrolithiasis]]: pain control, hydration (see [[Flank pain]])
 
==Disposition==
===Admit===
*Hemodynamic instability
*Ectopic pregnancy requiring intervention
*Ovarian torsion (to OR)
*Tubo-ovarian abscess
*Intractable pain or vomiting
*Sepsis from pelvic source
 
===Discharge===
*Stable patients with benign diagnosis (functional cyst, PID without TOA, mittelschmerz)
*Clear return precautions: worsening pain, fever, heavy bleeding, syncope
*Ensure appropriate follow-up (OB/GYN within 48-72 hours for PID)
*Ectopic precautions in early pregnancy with pregnancy of unknown location
 
==See Also==
*[[Prepubertal pelvic pain]]
*[[Abdominal Pain]]
*[[Abdominal Pain]]
*[[Ectopic pregnancy]]
*[[Ovarian torsion]]
*[[Pelvic inflammatory disease]]
*[[Vaginal bleeding]]
==External Links==
*[http://ddxof.com/acute-pelvic-pain-2/ DDxOf: Differential Diagnosis of Acute Pelvic Pain]


== Source ==
==References==
*Hardwood-Nuss
<references/>


[[Category:OB/GYN]]
[[Category:OBGYN]]
[[Category:Symptoms]]

Revisión actual - 09:35 22 mar 2026

This page is for adult patients. For pediatric patients, see: Prepubertal pelvic pain

Background


Classification by Abdominal pain location

Side-by-side comparison of quadrants and regions.
Chart of commonly reported referred pain sites.
RUQ pain Epigastric pain LUQ pain
Flank pain Diffuse abdominal pain Flank pain
RLQ pain Pelvic pain LLQ pain
Pelvic anatomy.

Clinical Features

Red Flags

  • Hemodynamic instability (consider ruptured ectopic pregnancy, hemorrhagic cyst, ruptured AAA)
  • Peritoneal signs (rebound, guarding, rigidity)
  • Fever with pelvic pain (consider tubo-ovarian abscess, PID, or other pelvic abscess)
  • Positive pregnancy test with pain (ectopic until proven otherwise)
  • Acute onset severe unilateral pain (consider ovarian torsion or testicular torsion)

History

  • Onset, duration, character, location, radiation, severity
  • Menstrual history: LMP, regularity, abnormal bleeding
  • Sexual history: activity, contraception, STI risk factors
  • Obstetric history: prior pregnancies, ectopics
  • Associated symptoms: vaginal bleeding/discharge, urinary symptoms, GI symptoms, fever
  • Surgical history: prior pelvic/abdominal surgeries

Physical Exam

  • Abdominal exam: tenderness, distension, peritoneal signs
  • Pelvic exam: cervical motion tenderness, adnexal tenderness/masses, vaginal discharge/bleeding
  • Consider rectal exam if indicated
  • Testicular exam in males with lower pelvic/groin complaints

Differential Diagnosis

Acute Pelvic Pain

Differential diagnosis of acute pelvic pain

Gynecologic/Obstetric

Genitourinary

Gastrointestinal

Musculoskeletal

Vascular

Postmenopausal Pelvic Pain

Gynecologic

Gastrointestinal

Urologic

Prepubescent-Urethral prolapse

Urologic

  • Sarcoma botryoides

Evaluation

Immediate

  • Urine pregnancy test (mandatory in all women of reproductive age)
  • Point-of-care ultrasound (POCUS) if hemodynamically unstable or concern for ectopic, free fluid, or torsion

Laboratory

  • CBC, BMP
  • Urinalysis, urine culture
  • Quantitative beta-hCG if pregnancy test positive
  • Gonorrhea/chlamydia testing (NAAT) if concern for PID or STI
  • ESR/CRP if concern for inflammatory process
  • Type and screen if significant bleeding or concern for ectopic

Imaging

  • Transvaginal ultrasound is the primary imaging modality for pelvic pain
    • Evaluate for intrauterine pregnancy, ectopic pregnancy, ovarian cyst/torsion, free fluid
  • CT abdomen pelvis if broad differential or concern for appendicitis, diverticulitis, or abscess
  • Consider MRI for suspected ovarian torsion with nondiagnostic ultrasound (especially in pregnancy)

Management

General

  • IV access, fluid resuscitation if hemodynamically unstable
  • Analgesia: ketorolac (if not pregnant), acetaminophen, opioids for severe pain
  • Antiemetics as needed

Condition-Specific

Disposition

Admit

  • Hemodynamic instability
  • Ectopic pregnancy requiring intervention
  • Ovarian torsion (to OR)
  • Tubo-ovarian abscess
  • Intractable pain or vomiting
  • Sepsis from pelvic source

Discharge

  • Stable patients with benign diagnosis (functional cyst, PID without TOA, mittelschmerz)
  • Clear return precautions: worsening pain, fever, heavy bleeding, syncope
  • Ensure appropriate follow-up (OB/GYN within 48-72 hours for PID)
  • Ectopic precautions in early pregnancy with pregnancy of unknown location

See Also

External Links

References

  1. Norris DL, Young JD. UTI. EM Clin N Am. 2008; 26:413-30.