Diferencia entre revisiones de «Tramadol»
(Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)) |
(Add See Also and References) |
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*Excretion: urine | *Excretion: urine | ||
*Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | *Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | ||
==See Also== | |||
*[[Opioids]] | |||
*[[Acute pain management]] | |||
*[[Serotonin syndrome]] | |||
*[[Seizure]] | |||
==References== | |||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
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|?Has Population=Population | |?Has Population=Population | ||
|format= | |format=table | ||
|headers=plain | |headers=plain | ||
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|sort=Has Indication | |sort=Has Indication | ||
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Revisión actual - 09:15 22 mar 2026
General
- Type: Opioid
- Dosage Forms: PO, IM, IV, PR; immediate and extended release formulations; combination formulations with acetaminophen (Tramacet)
- Common Trade Names: Ultram, Ryzolt, Zytram
Adult Dosing
General
- Moderate to severe pain:
- 50-100mg PO q4-6h PRN
- Chronic severe pain:
- 100-300mg ER PO daily
Pediatric Dosing
- Not Currently recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: Probably safe
- Renal Dosing
- Adult: CrCL < 30: given q12h, max 200mg/day
- Pediatric: none
- Hepatic Dosing
- Adult: cirrhosis: 50mg q12h, max 100mg/day
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- Asthma, acute
- Respiratory depression
- Severe hepatic impairment
- Severe renal impairment
- Acute alcohol intoxication
Adverse Reactions
Serious
- Respiratory Depression
- Suicidal ideation
- Seizures
- Anaphylaxis
- Serotonin syndrome
- Stevens-Johnson syndrome
Common
Pharmacology
- Half-life: 6.3 - 7.9 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake
See Also
References
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Acute pain management | 50-100 mg PO q4-6h | Step 2 - Moderate pain (mild opioid) | PO | Adult |