Diferencia entre revisiones de «Tramadol»
(Add See Also and References) |
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| (No se muestran 11 ediciones intermedias de 4 usuarios) | |||
| Línea 1: | Línea 1: | ||
==General== | ==General== | ||
*Type: Opioid | *Type: [[Opioid]] | ||
*Dosage Forms: PO, IM, IV, PR | *Dosage Forms: PO, IM, IV, PR; immediate and extended release formulations; combination formulations with acetaminophen (Tramacet) | ||
*Common Trade Names: Ultram, Ryzolt, Zytram | *Common Trade Names: Ultram, Ryzolt, Zytram | ||
==Adult Dosing== | ==Adult Dosing== | ||
===General=== | ===General=== | ||
* | *Moderate to severe pain: | ||
**50-100mg PO q4-6h PRN | **50-100mg PO q4-6h PRN | ||
*Chronic severe pain: | *Chronic severe pain: | ||
**100-300mg ER PO | **100-300mg ER PO daily | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
| Línea 27: | Línea 27: | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
* | *Asthma, acute | ||
* | *Respiratory depression | ||
* | *Severe hepatic impairment | ||
* | *Severe renal impairment | ||
* | *Acute alcohol intoxication | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Respiratory Depression | *Respiratory Depression | ||
* | *Suicidal ideation | ||
*Seizures | *[[Seizures]] | ||
* | *[[Anaphylaxis]] | ||
* | *[[Serotonin syndrome]] | ||
* | *[[Stevens-Johnson syndrome]] | ||
===Common=== | ===Common=== | ||
*Nausea | *[[Nausea]] | ||
*Rash | *[[Rash]] | ||
*Headache | *Headache | ||
*Fatigue | *Fatigue | ||
* | *Xerostomia | ||
* | *Constipation | ||
*Tremor | *Tremor | ||
* | *Insomnia | ||
==Pharmacology== | ==Pharmacology== | ||
| Línea 57: | Línea 57: | ||
*Excretion: urine | *Excretion: urine | ||
*Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | *Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake | ||
==See Also== | |||
*[[Opioids]] | |||
*[[Acute pain management]] | |||
*[[Serotonin syndrome]] | |||
*[[Seizure]] | |||
==References== | |||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Tramadol]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=table | |||
|headers=plain | |||
|mainlabel=- | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
Revisión actual - 09:15 22 mar 2026
General
- Type: Opioid
- Dosage Forms: PO, IM, IV, PR; immediate and extended release formulations; combination formulations with acetaminophen (Tramacet)
- Common Trade Names: Ultram, Ryzolt, Zytram
Adult Dosing
General
- Moderate to severe pain:
- 50-100mg PO q4-6h PRN
- Chronic severe pain:
- 100-300mg ER PO daily
Pediatric Dosing
- Not Currently recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: Probably safe
- Renal Dosing
- Adult: CrCL < 30: given q12h, max 200mg/day
- Pediatric: none
- Hepatic Dosing
- Adult: cirrhosis: 50mg q12h, max 100mg/day
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- Asthma, acute
- Respiratory depression
- Severe hepatic impairment
- Severe renal impairment
- Acute alcohol intoxication
Adverse Reactions
Serious
- Respiratory Depression
- Suicidal ideation
- Seizures
- Anaphylaxis
- Serotonin syndrome
- Stevens-Johnson syndrome
Common
Pharmacology
- Half-life: 6.3 - 7.9 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:exact mechanism unknown, binds to mu opioid receptors and weakly inhibits NE/Serotonin reuptake
See Also
References
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Acute pain management | 50-100 mg PO q4-6h | Step 2 - Moderate pain (mild opioid) | PO | Adult |