Diferencia entre revisiones de «Hydrocodone»
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==See Also== | |||
*[[Opioids]] | |||
*[[Acute pain management]] | |||
*[[Opioid overdose]] | |||
==References== | |||
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[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
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Revisión actual - 09:11 22 mar 2026
General
- Type: Opioid
- Dosage Forms: PO
- Common Trade Names: Zohydro, Hysingla
- Commonly combined with acetaminophen as Norco and Vicodin
Adult Dosing
General
- For Pain, severe chronic: Individualize dose PO q12h; start 10mg PO q12h, may increase by 10mg PO q12h q3-7 days. Titrate slowly in elderly patients.
Pediatric Dosing
- Currently not recommended
Special Populations
- Pregnancy Rating: C
- Lactation Risk Categories: possibly unsafe
- Renal Dosing
- Adult: none
- Pediatric: none
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- labor and delivery
- GI obstruction
- paralytic ileus
- acute asthma exacerbation
Adverse Reactions
Serious
- respiratory depression
- apnea
- hypotension, severe
- paralytic ileus
- bradycardia
- anaphylaxis
Common
- Constipation
- nausea
- fatigue
- vomiting
- xerostomia
- headache
- URI
- tremor
Pharmacology
- Half-life: 8 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action: bind to various opioid receptors
See Also
References
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Acute pain management | 5-10 mg PO q4-6h PRN (with acetaminophen 325 mg) | Step 2 - Moderate pain (mild opioid) | PO | Adult |