Diferencia entre revisiones de «Neuromuscular blocking agents»
m (Rossdonaldson1 moved page Neuromuscular blocker to Neuromuscular blocking agents) |
Sin resumen de edición |
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==Sources== | ==Sources== | ||
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[[Category:Drugs]] | |||
Revisión del 19:05 24 mar 2015
Background
- Non-depolarizing
- Competitively block binding of ACh to its receptors
- Depolarizing
- Depolarizing skeletal muscle fiber
- Persistent depolarization makes the muscle fiber resistant to further stimulation by ACh
Types
| Agent | Time to onset (seconds) | Duration (minutes) | Side effects |
|---|---|---|---|
| Non-Depolarizing | |||
| Succinylcholine | fasciculations, post-operative pain | ||
| Depolarizing | |||
| Vecuronium (Norcuron) | 60 | 30–40 | Few, may cause prolonged paralysis and promote muscarinic block |
| Rocuronium (Zemuron) | 75 | 45–70 | may promote muscarinic block |
| Pancuronium (Pavulon) | 90 | 180 or more |
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