Diferencia entre revisiones de «Neuromuscular blocking agents»

Revisión del 03:33 24 feb 2015

Non-depolarizing
- Competitively block binding of ACh to its receptors
Depolarizing
- Depolarizing skeletal muscle fiber
- Persistent depolarization makes the muscle fiber resistant to further stimulation by ACh

Neuromuscular Blocking Agents
Agent	Time to onset (seconds)	Duration (minutes)	Side effects
Non-Depolarizing
Succinylcholine			fasciculations, post-operative pain
Depolarizing
Atracurium (Tracrium)	90	30 min or less^[1]	hypotension, transiently,^[1] by release of histamine Toxic metabolite called laudanosine, greater accumulation in individuals with renal failure
Vecuronium (Norcuron)	60	30–40	Few, may cause prolonged paralysis and promote muscarinic block
Rocuronium (Zemuron)	75	45–70	may promote muscarinic block
Pancuronium (Pavulon)	90	180 or more	tachycardia (slight) (no hypotension)

↑ ^1.0 ^1.1 Error en la cita: Etiqueta <ref> no válida; no se ha definido el contenido de las referencias llamadas Rang151

Authors:

@@ Línea 10: / Línea 10: @@
 |+Neuromuscular Blocking Agents
 !Agent
-|'''Time to onset''' <br> (seconds)
+!'''Time to onset''' (seconds)
-|'''Duration''' <br> (minutes)
+!'''Duration''' (minutes)
 !Side effects
-!Clinical use
 |-
 | '''Non-Depolarizing'''
@@ Línea 47: / Línea 46: @@
 |
 *[[tachycardia]] (slight)
-(no hypotension)
+*(no hypotension)
 |-
 |}