Diferencia entre revisiones de «Sheehan's syndrome»
| Línea 22: | Línea 22: | ||
==Management== | ==Management== | ||
*Currently no treatment is available but there is an ongoing open-label | *Currently no treatment is available but there is an ongoing small open-label pilot study looking at using recombinant human prolactin | ||
==Disposition== | ==Disposition== | ||
Revisión del 18:03 7 oct 2021
Background
- Also known as postpartum hypopituitarism
- Caused by pituitary hypoperfusion and infarction usually in the setting of postpartum hemorrhage
- During pregnancy there is enlargement of the pituitary gland predisposing it to ischemia in low-flow states
Clinical Features
- Symptoms consistent with adrenal insufficiency, hypothyroidism and hypogonadism
- Inability to lactate
- Amenorrhea or oligomenorrhea
- Fatigue
- Cold intolerance
- Lethargy
- Weight loss
Differential Diagnosis
Evaluation
Workup
Diagnosis
Management
- Currently no treatment is available but there is an ongoing small open-label pilot study looking at using recombinant human prolactin