Diferencia entre revisiones de «Clozapine»

(new page)
 
(additional info)
Línea 2: Línea 2:
*Atypical antipsychotic
*Atypical antipsychotic
*Controls positive and negative symptoms of psychotic disorders
*Controls positive and negative symptoms of psychotic disorders
*Used for schizophrenia
*Off label use:
**Bipolar disorder
**Borderline personality disorder


==Complications==
==Complications==
*QT Prolongation
*QT Prolongation
*Myocarditis
*Agranulocytosis in 1%–2% of patients during initial treatment 3 months  
*Agranulocytosis in 1%–2% of patients during initial treatment 3 months  
**Highest ~3 months into treatment and then decreases  
**Highest ~3 months into treatment and then decreases  
Línea 11: Línea 16:
**Diabetes
**Diabetes
**Decreased seizure threshold
**Decreased seizure threshold
*"Other adverse cardiovascular and respiratory effects" <ref>"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.</ref>
*"Increased mortality in elderly patients with dementia-related psychosis"<ref>"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.</ref>


==Also See==
==Also See==
*[[Schizophrenia]]
*[[Schizophrenia]]
*[Antipsychotic Medications]
*[[Bipolar disorder]]
*[[Borderline personality disorder]]
*[[Antipsychotic Medications]]


==Sources==
==Sources==
*Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162
*Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162
*"Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.


[[Category:Psych]]
[[Category:Psych]]

Revisión del 13:29 9 feb 2015

Background

  • Atypical antipsychotic
  • Controls positive and negative symptoms of psychotic disorders
  • Used for schizophrenia
  • Off label use:
    • Bipolar disorder
    • Borderline personality disorder

Complications

  • QT Prolongation
  • Myocarditis
  • Agranulocytosis in 1%–2% of patients during initial treatment 3 months
    • Highest ~3 months into treatment and then decreases
  • Other potential side effects:
    • Dyslipidemia
    • Diabetes
    • Decreased seizure threshold
  • "Other adverse cardiovascular and respiratory effects" [1]
  • "Increased mortality in elderly patients with dementia-related psychosis"[2]

Also See

Sources

  • Lange Poisoning and Drug Overdose, 6th Ed., p. 443-4, 160-162
  • "Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.
  1. "Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.
  2. "Clozaril (Clozapine) drug description - FDA approved labeling for prescription drugs and medications at RxList". Rxlist.com. Retrieved 2008-10-09.