Diferencia entre revisiones de «Metoprolol»
| (No se muestran 13 ediciones intermedias de 8 usuarios) | |||
| Línea 1: | Línea 1: | ||
==General== | ==General== | ||
*Type: [[Beta blockers]] | *Type: [[Beta blockers]] | ||
*Dosage Forms: | *Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable | ||
*Common Trade Names: | *Common Trade Names: Lopressor | ||
==Adult Dosing== | ==Adult Dosing== | ||
====[[Hypertension]]==== | |||
* 50-200 mg PO bid | |||
====[[CHF]]==== | |||
* 12.5-100 mg PO bid | |||
====[[Migraine]] prophylaxis==== | |||
* 25-100 mg PO bid | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: | *Lactation: | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: No adjustment necessary | ||
**Pediatric | **Pediatric: No adjustment necessary | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: Not defined however consider reduced dose due to hepatic metabolism | ||
**Pediatric | **Pediatric: Not defined however consider reduced dose due to hepatic metabolism | ||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
* Sinus bradycardia | |||
* AV blocks | |||
* decompensated acute CHF | |||
* cardiogenic shock | |||
* hypotension | |||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
* [[CHF]] | |||
* bradycardia | |||
* AV block | |||
* bronchospasm | |||
===Common=== | ===Common=== | ||
* fatigue | |||
* dizziness | |||
* depression | |||
* dyspnea | |||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: 3-7 hours | ||
*Metabolism: | *Metabolism: Liver | ||
*Excretion: | *Excretion: Renal | ||
*Mechanism of Action: | *Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist | ||
==See Also== | ==See Also== | ||
| Línea 36: | Línea 57: | ||
*[[Calcium Channel Blocker Toxicity]] | *[[Calcium Channel Blocker Toxicity]] | ||
*[[Atrial Fibrillation with RVR]] | *[[Atrial Fibrillation with RVR]] | ||
*[[Beta blocker toxicity]] | |||
==References== | |||
<references/> | <references/> | ||
[[Category: | |||
[[Category:Pharmacology]] | |||
[[Category:Cardiology]] | |||
Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. | |||
Revisión actual - 20:28 20 feb 2021
General
- Type: Beta blockers
- Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable
- Common Trade Names: Lopressor
Adult Dosing
Hypertension
- 50-200 mg PO bid
CHF
- 12.5-100 mg PO bid
Migraine prophylaxis
- 25-100 mg PO bid
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation:
- Renal Dosing
- Adult: No adjustment necessary
- Pediatric: No adjustment necessary
- Hepatic Dosing
- Adult: Not defined however consider reduced dose due to hepatic metabolism
- Pediatric: Not defined however consider reduced dose due to hepatic metabolism
Contraindications
- Allergy to class/drug
- Sinus bradycardia
- AV blocks
- decompensated acute CHF
- cardiogenic shock
- hypotension
Adverse Reactions
Serious
- CHF
- bradycardia
- AV block
- bronchospasm
Common
- fatigue
- dizziness
- depression
- dyspnea
Pharmacology
- Half-life: 3-7 hours
- Metabolism: Liver
- Excretion: Renal
- Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist
See Also
References
Metoprolol: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.