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==Background==
==Background==
High >3.5
*High >3.5
*Magnesium is an effective calcium channel blocker both extracellularly and intracellularly<ref>Rizzo MA, Fisher M, Lock JP. Hypermagnesemic pseudocoma. Arch Intern Med. 1993;153(9):1130.</ref>
*Intracellular magnesium profoundly blocks several cardiac potassium channels.


==Diagnosis==
==Diagnosis==
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==See Also==
==See Also==
*[[Electrolyte Abnormalities (Main)]]
*[[Electrolyte Abnormalities (Main)]]
[[Hypomagnesemia]]


==Source ==
==Source ==

Revisión del 03:48 13 ene 2015

Background

  • High >3.5
  • Magnesium is an effective calcium channel blocker both extracellularly and intracellularly[1]
  • Intracellular magnesium profoundly blocks several cardiac potassium channels.

Diagnosis

  • 2–3 - Nausea
  • 3–4 - Somnolence
  • 4–8 - Loss of DTRs
  • 8–12 - Respiratory depression
  • 12–15 - Hypotension, heart block, Cardiac Arrest

DDX

  1. Renal Failure
  2. Lithium
  3. Volume depletion
  4. Rhabdo

Treatment

  1. IVF (NS)
  2. Furosemide 20-40mg IVP
  3. CaCl 10% 5mL IV over 5min

See Also

Hypomagnesemia

Source

Tintinalli

  1. Rizzo MA, Fisher M, Lock JP. Hypermagnesemic pseudocoma. Arch Intern Med. 1993;153(9):1130.