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''Treatment to cover both [[gonorrhea]] and [[chlamydia]]''
''Treatment to cover both [[gonorrhea]] and [[chlamydia]]''
====Uncomplicated Infection====
''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>
*[[Ceftriaxone]] 500mg IM once (if >150kg, 1g)<ref>[https://www.cdc.gov/mmwr/volumes/69/wr/mm6950a6.htm?s_cid=mm6950a6_w CDC: Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020]</ref>, '''PLUS'''
<br>
**[[Doxycycline]] 100mg PO BID x 7 days (non-pregnant) '''OR'''
<u>Standard</u><br>
**[[Azithromycin]] 1g PO once (if pregnant)
*Gonorrhea
**[[Ceftriaxone]] IM x 1
***500 mg, if weight <150 kg
***1 g, if weight ≥150 kg
*Chlamydia
**[[Doxycycline]] 100 mg PO BID x 7 days


====Cephalosporin Allergy====
<br>
*[[Gentamicin]] 240mg IM once '''PLUS'''
<u>Ceftriaxone contraindicated</u><br>
**[[Azithromycin]] 2g PO once
*Gonorrhea
*[[Cefixime]] 800mg oral once '''PLUS'''
**[[Gentamicin]] 240 mg IM x 1 '''PLUS''' [[azithromycin]] 2 g PO x 1, '''OR'''
**[[Doxycycline]] 100mg PO BID x 7 days (non-pregnant) '''OR'''
**[[Cefixime]] 800 mg PO x 1
**[[Azithromycin]] 1g PO once (if pregnant)
*Chlamydia^
**[[Doxycycline]] 100 mg PO BID x 7 days
 
^Additional chlamydia coverage only needed if treated with cefixime only


====Partner treatment====
====Partner treatment====
*[[Cefixime]] 800mg oral once '''PLUS'''
*Gonorrhea
**[[Doxycycline]] 100mg PO BID x 7 days (non-pregnant) '''OR'''
**[[Cefixime]] 800mg PO x 1
**[[Azithromycin]] 1g PO once (if pregnant)
**Nonpregnant: [[doxycycline]] 100mg PO BID x 7 days, '''OR'''
**Pregnant: [[azithromycin]] 1g PO x 1


====Recurrent or Persistent====
====Recurrent or Persistent====
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''Consider coverage of [[trichomonas]], among men who have sex with women''
''Consider coverage of [[trichomonas]], among men who have sex with women''
*Metronidazole 2 gm PO x 1, '''OR'''
*[[Metronidazole]] 2 gm PO x 1, '''OR'''
*Tinidazole 2 gm PO x 1
*[[Tinidazole]] 2 gm PO x 1

Revisión del 18:53 23 dic 2020

Treatment to cover both gonorrhea and chlamydia Typically, treatment for both gonorrhea and chlamydia is indicated, if one entity is suspected.

Standard

  • Gonorrhea
    • Ceftriaxone IM x 1
      • 500 mg, if weight <150 kg
      • 1 g, if weight ≥150 kg
  • Chlamydia


Ceftriaxone contraindicated

^Additional chlamydia coverage only needed if treated with cefixime only

Partner treatment

Recurrent or Persistent

Target M. genitalium

Consider coverage of trichomonas, among men who have sex with women