Diferencia entre revisiones de «Dilantin Load»
(Created page with "First time load: 18mg/kg (can be given PO in divided doses or IV) If patient is already on dilantin but sub-therapeutic use following to calculate dose needed to achieve ther...") |
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First time load | ==First time load== | ||
18mg/kg (can be given PO in divided doses or IV) | |||
==Already On== | |||
If patient is already on dilantin but sub-therapeutic use following to calculate dose needed to achieve therapeutic level: | If patient is already on dilantin but sub-therapeutic use following to calculate dose needed to achieve therapeutic level: | ||
Concentration adjusted = (concentration desired - concentration measured) x (0.7 x adjusted body weight) | Concentration adjusted = (concentration desired - concentration measured) x (0.7 x adjusted body weight) | ||
==Correcting== | |||
Sheiner-Tozer Equation may be needed to correct level in patients with low albumin or abnormal creatinine: | #Sheiner-Tozer Equation may be needed to correct level in patients with low albumin or abnormal creatinine: | ||
## Corrected level = measured level/[(adjustment x albumin) + 0.1] | |||
## adjustment is 0.2 unless patient has Creatinine clearance <20 then it is 0.1 | |||
==See Also== | ==See Also== | ||
Neuro: Seizure (Reloading) | Neuro: Seizure (Reloading) | ||
[[Category:Drugs]] | |||
[[Category:Neuro]] | [[Category:Neuro]] | ||
Revisión del 06:59 28 mar 2011
First time load
18mg/kg (can be given PO in divided doses or IV)
Already On
If patient is already on dilantin but sub-therapeutic use following to calculate dose needed to achieve therapeutic level:
Concentration adjusted = (concentration desired - concentration measured) x (0.7 x adjusted body weight)
Correcting
- Sheiner-Tozer Equation may be needed to correct level in patients with low albumin or abnormal creatinine:
- Corrected level = measured level/[(adjustment x albumin) + 0.1]
- adjustment is 0.2 unless patient has Creatinine clearance <20 then it is 0.1
See Also
Neuro: Seizure (Reloading)