Diferencia entre revisiones de «Parkinson's disease»
(Created page with "==Background== *Extrapyramidal movement disorder a/w reduced dopaminergic receptors in substantia nigra ==Clinical Features== *TRAP mnemonic: **Tremor (resting) ***Initially is ...") |
Sin resumen de edición |
||
| Línea 14: | Línea 14: | ||
***Impaired ability to turn or change direction while walking | ***Impaired ability to turn or change direction while walking | ||
==Treatment== | == Treatment == | ||
*Anticholinergics | |||
**Benztropine | *Anticholinergics | ||
*Dopamine agonists | **Benztropine | ||
**Levodopa | *Dopamine agonists | ||
**Levodopa | |||
**Bromocriptine | |||
==Source== | ==Source== | ||
Revisión del 19:47 5 nov 2012
Background
- Extrapyramidal movement disorder a/w reduced dopaminergic receptors in substantia nigra
Clinical Features
- TRAP mnemonic:
- Tremor (resting)
- Initially is unilateral tremor of upper extremity, esp finger and thumb ("pill rolling")
- Dissipates when intentional movement is performed
- Rigidity (cogwheel)
- Elicited by causing passive movement of limb through full range of motion
- Akinesia
- Slowness of voluntary movement
- Posture/equilibrium impairment
- Impaired ability to turn or change direction while walking
- Tremor (resting)
Treatment
- Anticholinergics
- Benztropine
- Dopamine agonists
- Levodopa
- Bromocriptine
Source
Tintinalli