Unfractionated heparin - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:55:44Z

Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T17:25:53Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T16:44:02Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

@@ Línea 62: / Línea 62: @@
 **Unpredictable anticoagulation effect
 **Must monitor with PTT; therapeutic range is 1.5-2.5x normal value
 ==See Also==

2023-01-25T17:56:34Z

Adult Dosing

← Revisión anterior		Revisión del 17:56 25 ene 2023
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	==Adult Dosing==		==Adult Dosing==
	*See [https://depts.washington.edu/anticoag/home/content/heparin-infusion-guidelines University of Washington pharmacy heparin infusion guidelines]
	===Thromboembolism===		===Thromboembolism===
	*Bolus: 80 units/kg IV x 1 (MAX: 5,000 units)		*Bolus: 80 units/kg IV x 1 (MAX: 5,000 units)

2023-01-13T04:47:05Z

Added lower dose ACS dosing (from https://depts.washington.edu/anticoag/home/content/heparin-infusion-guidelines)

← Revisión anterior		Revisión del 04:47 13 ene 2023
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	*Bolus: 80 units/kg IV x 1 (MAX: 5,000 units)		*Bolus: 80 units/kg IV x 1 (MAX: 5,000 units)
	*Then drip: 18 units/kg/h IV (MAX: 1,000 units/h)		*Then drip: 18 units/kg/h IV (MAX: 1,000 units/h)
			*Adjust dose to target aPTT levels based on nomogram

			===Acute Coronary Syndrome===
			*Bolus: 50 units/kg IV x 1 (MAX: 5,000 units)
			*Then drip: 12 units/kg/h IV (MAX: 1,000 units/h)
	*Adjust dose to target aPTT levels based on nomogram		*Adjust dose to target aPTT levels based on nomogram

2022-10-01T19:53:14Z

Adverse Reactions

← Revisión anterior		Revisión del 19:53 1 oct 2022
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	*Thrombocytopenia		*Thrombocytopenia

	===Common===<ref>Warnock LB, Huang D. Heparin. [Updated 2022 Jul 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538247/</ref>		===Common===
	*Injection site reaction		*Injection site reaction<ref>Warnock LB, Huang D. Heparin. [Updated 2022 Jul 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538247/</ref>
	*Hyperkalemia		*Hyperkalemia
	*Alopecia		*Alopecia

2022-10-01T19:52:50Z

Adverse Reactions

← Revisión anterior		Revisión del 19:52 1 oct 2022
Línea 42:		Línea 42:
	*Thrombocytopenia		*Thrombocytopenia

	===Common===		===Common===<ref>Warnock LB, Huang D. Heparin. [Updated 2022 Jul 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538247/</ref>
	*Injection site ~~reactions~~		*Injection site reaction
	*Hyperkalemia		*Hyperkalemia
	*Alopecia		*Alopecia

2022-10-01T19:50:12Z

@@ Línea 36: / Línea 36: @@
 *Liver failure
 *Concurrent use of warfarin, fibrinolytics, steroids, or antiplatelet drugs
 ==Pharmacology==

2021-02-21T02:41:07Z

Contraindications

← Revisión anterior		Revisión del 02:41 21 feb 2021
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	*Allergy to class/drug		*Allergy to class/drug
	*33% of patients develop some form of bleeding complication; 2-6% develop major bleeding		*33% of patients develop some form of bleeding complication; 2-6% develop major bleeding
	*~~Heparin-Induced Thrombocytopenia~~		*[[HIT (Heparin-Induced Thrombocytopenia)]]
	*See [[HIT (Heparin-Induced Thrombocytopenia)]]

	===Risk Factors for Major Bleeding Complication===		===Risk Factors for Major Bleeding Complication===

2019-09-19T17:25:48Z

General