Sumatriptan - Revision history

Danbot: Add MedicationDose SMW query table for dynamic indications

2026-03-20T22:34:55Z

Add MedicationDose SMW query table for dynamic indications

@@ Línea 52: / Línea 52: @@
 ==Comments==
 ==See Also==
 *[[Headache]]

Bouspret: /* Adult Dosing */

2019-10-24T03:49:28Z

Adult Dosing

← Revisión anterior		Revisión del 03:49 24 oct 2019
Línea 7:		Línea 7:
	==Adult Dosing==		==Adult Dosing==
	*Intranasal spray: 5-20 mg, may repeat dose if headache persists after 2 hours		*Intranasal spray: 5-20 mg, may repeat dose if headache persists after 2 hours
			*Oral: Initial: 50 to 100 mg once. If initial dose was partially effective or headache recurs, may repeat a dose (usually same as first dose) after ≥2 hours. Maximum dose: 100 mg per dose; 200 mg per 24 hours.

	==Pediatric Dosing==		==Pediatric Dosing==

Bmurray990: /* Pediatric Dosing */

2019-01-26T19:14:31Z

Pediatric Dosing

← Revisión anterior		Revisión del 19:14 26 ene 2019
Línea 12:		Línea 12:
	**5-17 years: 5mg-20mg administered in one nostril as a single dose		**5-17 years: 5mg-20mg administered in one nostril as a single dose
	*SubQ:		*SubQ:
	**6-71 years: 3-6mg single dose		**6-17 years: 3-6mg single dose
	*Efficacy of oral dosing has not been demonstrated in patients <17 years old.		*Efficacy of oral dosing has not been demonstrated in patients <17 years old.

Bmurray990: /* Pediatric Dosing */

2019-01-26T19:14:16Z

Pediatric Dosing

← Revisión anterior		Revisión del 19:14 26 ene 2019
Línea 9:		Línea 9:

	==Pediatric Dosing==		==Pediatric Dosing==
	~~''Safety/efficacy~~ not ~~established''~~		*Intranasal:
			**5-17 years: 5mg-20mg administered in one nostril as a single dose
			*SubQ:
			**6-71 years: 3-6mg single dose
			*Efficacy of oral dosing has not been demonstrated in patients <17 years old.

	==Special Populations==		==Special Populations==

Rossdonaldson1: /* Adverse Reactions */

2016-09-24T10:54:49Z

Adverse Reactions

← Revisión anterior		Revisión del 10:54 24 sep 2016
Línea 28:		Línea 28:
	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*MI, hypertensive crisis, ventricular arrhythmias, vasospasm		*[[MI]], [[hypertensive crisis]], ventricular arrhythmias, vasospasm
	*Serotonin syndrome		*[[Serotonin syndrome]]
	*Stroke, intracranial hemorrhage, seizure		*[[Stroke]], [[intracranial hemorrhage]], [[seizure]]
	*Visual loss		*[[Visual loss]]

	===Common===		===Common===
	*Dizziness		*[[Dizziness]]
	*Nausea/vomiting		*[[Nausea/vomiting]]
	*URI symptoms		*[[URI]] symptoms

	==Pharmacology==		==Pharmacology==

ClaireLewis: Created page with "==Administration== Type: Ergotamine anti-migraine drug Dosage Forms: Routes of Administration: Intranasal, oral, subcutanous, transdermal Common Trade Names: Imitrex ==Ad..."

2016-09-11T00:00:57Z

Created page with "==Administration== *Type: Ergotamine anti-migraine drug *Dosage Forms: *Routes of Administration: Intranasal, oral, subcutanous, transdermal *Common Trade Names: Imitrex ==Ad..."

Página nueva

==Administration==
*Type: Ergotamine anti-migraine drug
*Dosage Forms:
*Routes of Administration: Intranasal, oral, subcutanous, transdermal
*Common Trade Names: Imitrex

==Adult Dosing==
*Intranasal spray: 5-20 mg, may repeat dose if headache persists after 2 hours

==Pediatric Dosing==
''Safety/efficacy not established''

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation risk categories|Lactation risk]]: infant risk minimal
*Renal dosing: no adjustment
*Hepatic dosing: contraindicated in severe hepatic impairment

==Contraindications==
*Allergy to class/drug
*MAOI use concomitantly or within 2 weeks
*Concomitant use of ergotamine-containing/ergot-type medication within 24 hours
*Use of another 5-HT agonist within 24 hours
*History of cardiovascular (including arrythmias, CAD, uncontrolled hypertension), peripheral vascular, or ischemic bowel disease
*History of stroke/TIA or hemiplegic/basilar migraine
*Severe hepatic impairment

==Adverse Reactions==
===Serious===
*MI, hypertensive crisis, ventricular arrhythmias, vasospasm
*Serotonin syndrome
*Stroke, intracranial hemorrhage, seizure
*Visual loss

===Common===
*Dizziness
*Nausea/vomiting
*URI symptoms

==Pharmacology==
*Half-life: 2-3 hours
*Metabolism: Hepatic via monamine oxidase (mostly MAO-A)
*Excretion: mostly renal

==Mechanism of Action==
*Cranial vessel constriction, 5HT agonist, inhibition of pro-inflammatory neuropeptide release
==Comments==

==See Also==
*[[Headache]]
*[[Serotonin syndrome]]
==References==
<references/>
[[Category:Pharmacology]]

Sumatriptan - Revision history

Danbot: Add MedicationDose SMW query table for dynamic indications

Bouspret: /* Adult Dosing */

Bmurray990: /* Pediatric Dosing */

Bmurray990: /* Pediatric Dosing */

Rossdonaldson1: /* Adverse Reactions */

ClaireLewis: Created page with "==Administration== *Type: Ergotamine anti-migraine drug *Dosage Forms: *Routes of Administration: Intranasal, oral, subcutanous, transdermal *Common Trade Names: Imitrex ==Ad..."

ClaireLewis: Created page with "==Administration== Type: Ergotamine anti-migraine drug Dosage Forms: Routes of Administration: Intranasal, oral, subcutanous, transdermal Common Trade Names: Imitrex ==Ad..."