https://wikem.org/w/index.php?action=history&feed=atom&title=Sulfasalazine 2026-04-19T03:44:27Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Sulfasalazine&diff=229734&oldid=prev 2019-09-23T22:38:09Z

<p><span dir="auto"><span class="autocomment">Special Populations</span></span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="es"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisión anterior</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisión del 22:38 23 sep 2019</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Línea 27:</td> <td colspan="2" class="diff-lineno">Línea 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Special Populations==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Special Populations==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*[[Drug pregnancy categories|Pregnancy Rating]]: <del style="font-weight: bold; text-decoration: none;">Benefits </del>outweigh risk during pregnancy; low risk</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*[[Drug pregnancy categories|Pregnancy Rating]]: <ins style="font-weight: bold; text-decoration: none;">Category B, benefits </ins>outweigh risk during pregnancy; low risk</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Lactation risk: Caution advised; risk of infant diarrhea</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Lactation risk: Caution advised; risk of infant diarrhea</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> </table>

ClaireLewis https://wikem.org/w/index.php?title=Sulfasalazine&diff=170507&oldid=prev 2018-01-12T19:20:54Z

<p>Creation of Page</p> <p><b>Página nueva</b></p><div>==Administration==<br /> *Type: [[Salicylate]]<br /> *Dosage Forms: Tab: 500mg; DR Tab: 500mg<br /> *Routes of Administration: Oral<br /> *Common Trade Names: Azulfidine, Azulfidine EN-tabs, Sulfazine<br /> <br /> ==Adult Dosing==<br /> ===[[Ulcerative Colitis]]===<br /> *500 mg PO q6h<br /> **Max: 6 g/day<br /> ===[[Rheumatoid arthritis]]===<br /> *1 g PO q12h<br /> **Max 4 g/day<br /> ===[[Crohn's disease]]===<br /> *500 mg PO q6h<br /> **Max 6 g/day<br /> <br /> ==Pediatric Dosing==<br /> ===[[Ulcerative Colitis]]===<br /> *6+ years old<br /> **30-70 mg/kg/day PO divided q12h<br /> ***Max: 2 g/day<br /> ===[[Juvenile idiopathic arthritis]]===<br /> *6+ years old<br /> **30-50 mg/kg/day PO divided q12h<br /> ***Max: 2 g/day<br /> <br /> ==Special Populations==<br /> *[[Drug pregnancy categories|Pregnancy Rating]]: Benefits outweigh risk during pregnancy; low risk<br /> *Lactation risk: Caution advised; risk of infant diarrhea<br /> <br /> ===Renal Dosing===<br /> *Adult: Not defined<br /> *Pediatric: Not defined<br /> ===Hepatic Dosing===<br /> *Adult: Not defined<br /> *Pediatric: Not defined<br /> <br /> ==Contraindications==<br /> *Allergy to class/drug<br /> *Hypersensitivity to [[salicylates]]<br /> *Hypersensitivity to [[sulfonamides]]<br /> *[[Porphyria]]<br /> *GI Obstruction, GU obstruction<br /> *Febrile viral infection (pts &lt;20 yo)<br /> <br /> ==Adverse Reactions==<br /> ===Serious===<br /> *Hypersensitivity reaction, [[anaphylaxis]]<br /> *Erythema multiforme<br /> *[[Stevens-Johnson syndrome]], [[Toxic epidermal necrolysis]]<br /> *Pulmonary toxicity, hepatotoxicity, nephrotoxicity<br /> *[[Pancreatitis]]<br /> *[[Seizure]]<br /> *[[Meningitis]]<br /> *[[Agranulocytosis]], [[Aplastic anemia]], [[hemolytic anemia]]<br /> *Infertility, Oligospermia<br /> *[[Reye syndrome]]<br /> *[[Hypoglycemia]]<br /> <br /> ===Common===<br /> *Anorexia<br /> *[[Headache]], [[Nausea]], [[Vomiting]], [[Dizziness]]<br /> *[[Dyspepsia]], stomatitis<br /> *Oligospermia<br /> *[[Rash]], [[Pruritus]], Urticaria<br /> *[[Abdominal pain]]<br /> *[[Fever]]<br /> *[[Leukopenia]], [[hemolytic anemia]]<br /> *Cyanosis<br /> *Crystalluria, [[Hematuria]]<br /> *Photosensitivity<br /> <br /> ==Pharmacology==<br /> *Half-life: 7.6 h (Active metabolites 10.4-14.8h)<br /> *Metabolism: GI tract, liver<br /> *Excretion: Urine 37% (15% unchanged), feces<br /> <br /> ==Mechanism of Action==<br /> *Blocks cyclooxygenase and inhibits prostaglandin production, producing anti-inflammatory effects<br /> <br /> ==Comments==<br /> <br /> <br /> ==See Also==<br /> <br /> <br /> ==References==<br /> &lt;references/&gt;<br /> <br /> [[Category:Pharmacology]]</div>

Jonwarren