Strongyloides stercoralis - Revision history

Danbot: Add Ivermectin AntibioticDose entry

2026-03-20T11:01:24Z

Add Ivermectin AntibioticDose entry

← Revisión anterior		Revisión del 11:01 20 mar 2026
Línea 1:		Línea 1:
	<languages/>		<languages/>
	~~<translate>~~

	==Background==		==Background==
Línea 18:		Línea 18:
	===Risk factors===		===Risk factors===

	*[[~~Special:MyLanguage/~~Corticosteroid\|Corticosteroid]] use, immunosuppression		*[[Corticosteroid\|Corticosteroid]] use, immunosuppression
	*[[~~Special:MyLanguage/~~transplant complications\|Transplantation]]		*[[transplant complications\|Transplantation]]
	*Hematologic neoplasm (e.g. [[~~Special:MyLanguage/~~leukemia\|leukemia]])		*Hematologic neoplasm (e.g. [[leukemia\|leukemia]])
	*Human T-lymphotropic virus-1 infection (HTLV-1)		*Human T-lymphotropic virus-1 infection (HTLV-1)
	*[[~~Special:MyLanguage/~~Malnutrition\|Malnutrition]]		*[[Malnutrition\|Malnutrition]]
	*[[~~Special:MyLanguage/~~Diabetes\|Diabetes]]		*[[Diabetes\|Diabetes]]
	*Chronic [[~~Special:MyLanguage/~~renal failure\|renal failure]]		*Chronic [[renal failure\|renal failure]]
	*Chronic [[~~Special:MyLanguage/~~alcohol Abuse\|alcohol use]]		*Chronic [[alcohol Abuse\|alcohol use]]


Línea 37:		Línea 37:
	*Asymptomatic in up to 60% of those infected<ref>Greaves D, Coggle S, Pollar C, Aliyu SH, Moore EM. Strongyloides stercoralis infection. BMJ 2013;347:f4610 doi: 10.1136/bmj.f4610 (Published 30 July 2013).</ref>		*Asymptomatic in up to 60% of those infected<ref>Greaves D, Coggle S, Pollar C, Aliyu SH, Moore EM. Strongyloides stercoralis infection. BMJ 2013;347:f4610 doi: 10.1136/bmj.f4610 (Published 30 July 2013).</ref>
	*Nonspecific GI complaints are most common presentation		*Nonspecific GI complaints are most common presentation
	**Weight loss, [[~~Special:MyLanguage/~~diarrhea\|diarrhea]], [[~~Special:MyLanguage/~~abdominal pain\|abdominal pain]], [[~~Special:MyLanguage/~~vomiting\|vomiting]]		**Weight loss, [[diarrhea\|diarrhea]], [[abdominal pain\|abdominal pain]], [[vomiting\|vomiting]]

	===Dermatologic===		===Dermatologic===

	*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae		*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae
	*Perianal [[~~Special:MyLanguage/~~pruritus\|pruritus]]		*Perianal [[pruritus\|pruritus]]
	*Foot [[~~Special:MyLanguage/~~pruritus\|pruritus]] (“ground itch”)		*Foot [[pruritus\|pruritus]] (“ground itch”)


	===Respiratory===		===Respiratory===

	*Dry [[~~Special:MyLanguage/~~cough\|cough]]		*Dry [[cough\|cough]]
	*[[~~Special:MyLanguage/~~Wheezing\|Wheezing]]		*[[Wheezing\|Wheezing]]
	*Loeffler’s-like syndrome: [[~~Special:MyLanguage/~~fever\|fever]], [[~~Special:MyLanguage/~~shortness of breath\|shortness of breath]], [[~~Special:MyLanguage/~~wheezing\|wheezing]], pulmonary infiltrates		*Loeffler’s-like syndrome: [[fever\|fever]], [[shortness of breath\|shortness of breath]], [[wheezing\|wheezing]], pulmonary infiltrates


Línea 61:		Línea 61:
	==Differential Diagnosis==		==Differential Diagnosis==

	*[[~~Special:MyLanguage/~~Inflammatory bowel disease\|Inflammatory bowel disease]]		*[[Inflammatory bowel disease\|Inflammatory bowel disease]]
	*[[~~Special:MyLanguage/~~Schistosomiasis\|Schistosomiasis]]		*[[Schistosomiasis\|Schistosomiasis]]
	*[[~~Special:MyLanguage/~~Filariasis\|Filariasis]]		*[[Filariasis\|Filariasis]]
	*[[~~Special:MyLanguage/~~Hookworm\|Hookworm]]		*[[Hookworm\|Hookworm]]
	*[[~~Special:MyLanguage/~~Toxocara canis\|Toxocara canis]]		*[[Toxocara canis\|Toxocara canis]]
	*[[~~Special:MyLanguage/~~Atopic dermatitis\|Atopic dermatitis]]		*[[Atopic dermatitis\|Atopic dermatitis]]
	*[[~~Special:MyLanguage/~~Asthma\|Asthma]]		*[[Asthma\|Asthma]]
	*Allergic bronchopulmonary [[~~Special:MyLanguage/~~aspergillosis\|aspergillosis]]		*Allergic bronchopulmonary [[aspergillosis\|aspergillosis]]
	*[[~~Special:MyLanguage/~~Coccidioidomycosis\|Coccidioidomycosis]]		*[[Coccidioidomycosis\|Coccidioidomycosis]]
	*[[~~Special:MyLanguage/~~HIV\|HIV]]		*[[HIV\|HIV]]
	*[[~~Special:MyLanguage/~~Churg-Strauss syndrome\|Churg-Strauss syndrome]]		*[[Churg-Strauss syndrome\|Churg-Strauss syndrome]]
	*Eosinophilic [[~~Special:MyLanguage/~~leukemia\|leukemia]]		*Eosinophilic [[leukemia\|leukemia]]


Línea 80:		Línea 80:
	*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides		*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides
	**Complicated strongyloidiasis: blood/sputum cultures, in addition to above		**Complicated strongyloidiasis: blood/sputum cultures, in addition to above
	*Notable [[~~Special:MyLanguage/~~eosinophilia\|eosinophilia]] in up to 70% of cases, though can be absent in immunosuppressed		*Notable [[eosinophilia\|eosinophilia]] in up to 70% of cases, though can be absent in immunosuppressed
	*Gram negative bacteremia may be present in immunocompromised		*Gram negative bacteremia may be present in immunocompromised

Línea 89:		Línea 89:
	===Uncomplicated strongyloidiasis, normal immune system===		===Uncomplicated strongyloidiasis, normal immune system===

	*[[~~Special:MyLanguage/~~Ivermectin\|Ivermectin]] 200 mcg/kg daily x 1-2d (drug of choice)		*[[Ivermectin\|Ivermectin]] 200 mcg/kg daily x 1-2d (drug of choice)
	'''OR'''		'''OR'''
	*[[~~Special:MyLanguage/~~Albendazole\|Albendazole]] 400mg BID x 7d		*[[Albendazole\|Albendazole]] 400mg BID x 7d
	*Can consider albendazole prophylaxis in immigrants from endemic regions with consistent clinical presentation		*Can consider albendazole prophylaxis in immigrants from endemic regions with consistent clinical presentation

Línea 97:		Línea 97:
	===Immunosuppressed===		===Immunosuppressed===

	*Combination therapy: [[~~Special:MyLanguage/~~albendazole\|albendazole]] 400mg BID x 7d AND [[~~Special:MyLanguage/~~ivermectin\|ivermectin]] 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>		*Combination therapy: [[albendazole\|albendazole]] 400mg BID x 7d AND [[ivermectin\|ivermectin]] 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>
	*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />		*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />



			===Antibiotic Dosing===
			*{{AntibioticDose\|drug=Ivermectin\|dose=0.2mg/kg PO x1\|context=Strongyloidiasis\|disease=Strongyloides stercoralis\|population=Adult}}

	==Disposition==		==Disposition==
Línea 114:		Línea 118:
	[[Category:ID]]		[[Category:ID]]
	[[Category:GI]]		[[Category:GI]]
	~~</translate>~~

Ostermayer: Prepared the page for translation

2026-01-04T23:59:54Z

Prepared the page for translation

Show changes

ClaireLewis at 04:15, 30 September 2019

2019-09-30T04:15:20Z

← Revisión anterior		Revisión del 04:15 30 sep 2019
Línea 11:		Línea 11:

	===Risk factors===		===Risk factors===
	*Corticosteroid use, immunosuppression		*[[Corticosteroid]] use, immunosuppression
	*Transplantation		*[[transplant complications\|Transplantation]]
	*Hematologic neoplasm		*Hematologic neoplasm (e.g. [[leukemia]])
	*Human T-lymphotropic virus-1 infection (HTLV-1)		*Human T-lymphotropic virus-1 infection (HTLV-1)
	*Malnutrition		*[[Malnutrition]]
	*Diabetes		*[[Diabetes]]
	*Chronic renal failure		*Chronic [[renal failure]]
	*Chronic alcohol use		*Chronic [[alcohol Abuse\|alcohol use]]

	===Clinical significance===		===Clinical significance===
Línea 33:		Línea 33:

	===Respiratory===		===Respiratory===
	*Dry cough		*Dry [[cough]]
	*Wheezing		*[[Wheezing]]
	*Loeffler’s-like syndrome: fever, shortness of breath, wheezing, pulmonary infiltrates		*Loeffler’s-like syndrome: [[fever]], [[shortness of breath]], [[wheezing]], pulmonary infiltrates

	====Immunocompromised patients====		====Immunocompromised patients====
Línea 49:		Línea 49:
	*[[Atopic dermatitis]]		*[[Atopic dermatitis]]
	*[[Asthma]]		*[[Asthma]]
	*Allergic bronchopulmonary aspergillosis		*Allergic bronchopulmonary [[aspergillosis]]
	*[[Coccidioidomycosis]]		*[[Coccidioidomycosis]]
	*[[HIV]]		*[[HIV]]
	*[[Churg-Strauss syndrome]]		*[[Churg-Strauss syndrome]]
	*Eosinophilic leukemia]		*Eosinophilic [[leukemia]]

	==Evaluation==		==Evaluation==
Línea 70:		Línea 70:

	===Immunosuppressed===		===Immunosuppressed===
	*Combination therapy: albendazole 400mg BID x 7d AND ivermectin 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>		*Combination therapy: [[albendazole]] 400mg BID x 7d AND [[ivermectin]] 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>
	*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />		*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />

Neil.m.young: Text replacement - "pruritis" to "pruritus"

2016-10-27T18:04:34Z

Text replacement - "pruritis" to "pruritus"

← Revisión anterior		Revisión del 18:04 27 oct 2016
Línea 29:		Línea 29:
	===Dermatologic===		===Dermatologic===
	*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae		*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae
	*Perianal [[~~pruritis~~]]		*Perianal [[pruritus]]
	*Foot [[pruritus]] (“ground itch”)		*Foot [[pruritus]] (“ground itch”)

ClaireLewis: /* Dermatologic */

2016-10-05T05:12:49Z

Dermatologic

← Revisión anterior		Revisión del 05:12 5 oct 2016
Línea 29:		Línea 29:
	===Dermatologic===		===Dermatologic===
	*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae		*Larva currens: rapidly progressive pruritic linear eruption due to migration of larvae
	*Perianal pruritis		*Perianal [[pruritis]]
	*Foot pruritus (“ground itch”)		*Foot [[pruritus]] (“ground itch”)

	===Respiratory===		===Respiratory===
	*Dry cough		*Dry cough

ClaireLewis: /* Evaluation */

2016-10-05T05:06:51Z

Evaluation

← Revisión anterior		Revisión del 05:06 5 oct 2016
Línea 58:		Línea 58:
	*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides		*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides
	**Complicated strongyloidiasis: blood/sputum cultures, in addition to above		**Complicated strongyloidiasis: blood/sputum cultures, in addition to above
	*Notable eosinophilia in up to 70% of cases, though can be absent in immunosuppressed		*Notable [[eosinophilia]] in up to 70% of cases, though can be absent in immunosuppressed
	*Gram negative bacteremia may be present in immunocompromised		*Gram negative bacteremia may be present in immunocompromised

Neil.m.young: Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

2016-07-28T02:14:17Z

Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

← Revisión anterior		Revisión del 02:14 28 jul 2016
Línea 54:		Línea 54:
	*Eosinophilic leukemia]		*Eosinophilic leukemia]

	==~~Diagnostic~~ Evaluation==		==Evaluation==
	*Establish possibility of infection (travel to endemic areas, etc)		*Establish possibility of infection (travel to endemic areas, etc)
	*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides		*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-20T12:19:31Z

Text replacement - "0 mg" to "0mg"

← Revisión anterior		Revisión del 12:19 20 jul 2016
Línea 65:		Línea 65:
	*[[Ivermectin]] 200 mcg/kg daily x 1-2d (drug of choice)		*[[Ivermectin]] 200 mcg/kg daily x 1-2d (drug of choice)
	'''OR'''		'''OR'''
	*[[Albendazole]] ~~400 mg~~ BID x 7d		*[[Albendazole]] 400mg BID x 7d
	*Can consider albendazole prophylaxis in immigrants from endemic regions with consistent clinical presentation		*Can consider albendazole prophylaxis in immigrants from endemic regions with consistent clinical presentation

	===Immunosuppressed===		===Immunosuppressed===
	*Combination therapy: albendazole ~~400 mg~~ BID x 7d AND ivermectin 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>		*Combination therapy: albendazole 400mg BID x 7d AND ivermectin 200 mcg/kg daily x 1-2d<ref name="treat">Feely NM, Waghorn DJ, Dexter T, Gallen I, Chiodini. Strongyloides stercoralis hyperinfection: difficulties in diagnosis and treatment. Anaesthesia 2010; 65: 298-301.</ref>
	*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />		*Antibiotics may need to be continued until there is evidence that parasite is cleared<ref name="treat" />

Rossdonaldson1: Text replacement - "SOB" to "shortness of breath"

2016-07-15T20:18:22Z

Text replacement - "SOB" to "shortness of breath"

← Revisión anterior		Revisión del 20:18 15 jul 2016
Línea 34:		Línea 34:
	*Dry cough		*Dry cough
	*Wheezing		*Wheezing
	*Loeffler’s-like syndrome: fever, ~~SOB~~, wheezing, pulmonary infiltrates		*Loeffler’s-like syndrome: fever, shortness of breath, wheezing, pulmonary infiltrates

	====Immunocompromised patients====		====Immunocompromised patients====

ClaireLewis: /* Diagnostic Evaluation */

2016-07-15T00:35:29Z

Diagnostic Evaluation

← Revisión anterior		Revisión del 00:35 15 jul 2016
Línea 57:		Línea 57:
	*Establish possibility of infection (travel to endemic areas, etc)		*Establish possibility of infection (travel to endemic areas, etc)
	*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides		*Uncomplicated strongyloidiasis: 3 serial stool samples screened for ova and parasites, as well as ELISA for Strongyloides
	**Complicated strongyloidiasis: blood/sputum Cx, in addition to above		**Complicated strongyloidiasis: blood/sputum cultures, in addition to above
	*Notable eosinophilia in up to 70% of cases, though can be absent in immunosuppressed		*Notable eosinophilia in up to 70% of cases, though can be absent in immunosuppressed
	*Gram negative bacteremia may be present in immunocompromised		*Gram negative bacteremia may be present in immunocompromised

	==Management==		==Management==