Plasmapheresis - Revision history

ClaireLewis: /* Indications */

2020-10-29T16:41:04Z

Indications

← Revisión anterior		Revisión del 16:41 29 oct 2020
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	**[[Hyperviscosity syndrome]]		**[[Hyperviscosity syndrome]]
	**[[Diffuse alveolar hemorrhage]] due to [[Goodpasture syndrome]]		**[[Diffuse alveolar hemorrhage]] due to [[Goodpasture syndrome]]
	**Chronic inflammatory demyelinating polyneuropathy		**[[Chronic inflammatory demyelinating polyneuropathy]]
	**Severe [[autoimmune hemolytic anemia]]		**Severe [[autoimmune hemolytic anemia]]
	*Indications for which plasmapheresis is accepted second-line therapy:		*Indications for which plasmapheresis is accepted second-line therapy:

ClaireLewis at 17:23, 1 October 2019

2019-10-01T17:23:21Z

← Revisión anterior		Revisión del 17:23 1 oct 2019
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	==Contraindications==		==Contraindications==
	*Hemodynamic instability, sepsis, or other conditions causing inability to tolerate fluid shifts		*[[shock\|Hemodynamic instability]], [[sepsis]], or other conditions causing inability to tolerate fluid shifts
	*Inability to tolerate central line placement		*Inability to tolerate central line placement
	*Allergy to [[FFP]] or albumin		*Allergy to [[FFP]] or albumin
Línea 54:		Línea 54:
	**[[Sepsis]]		**[[Sepsis]]
	**[[Transfusion infections]]		**[[Transfusion infections]]
	*~~Immunosupression~~		*Immunosuppression
	*[[Hypocalcemia]]		*[[Hypocalcemia]]
	*Complications of [[central line]] placement		*Complications of [[central line]] placement

ClaireLewis: /* Complications */

2019-08-28T17:35:53Z

Complications

← Revisión anterior		Revisión del 17:35 28 ago 2019
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	**[[Fluid overload]]		**[[Fluid overload]]
	**[[Sepsis]]		**[[Sepsis]]
	**[[Transfusion ~~Infections~~]]		**[[Transfusion infections]]
	*Immunosupression		*Immunosupression
	*[[Hypocalcemia]]		*[[Hypocalcemia]]

ClaireLewis: Created page with "==Overview== Involves extracorporeal separation of blood products, resulting in filtered plasma product Patient's plasma is removed, blood cells re-infused, and (usually) do..."

2017-04-03T17:48:30Z

Created page with "==Overview== *Involves extracorporeal separation of blood products, resulting in filtered plasma product *Patient's plasma is removed, blood cells re-infused, and (usually) do..."

Página nueva

==Overview==
*Involves extracorporeal separation of blood products, resulting in filtered plasma product
*Patient's plasma is removed, blood cells re-infused, and (usually) donor plasma transfused
*In US and other high-resourced settings, separation typically done by automated centrifuge

==Indications==
*Established indications for plasmapheresis as first-line treatment (either alone or in conjunction with other agents)
**[[Guillain-Barre syndrome]]
**[[Thrombotic thrombocytopenic purpura]]
**[[Myasthenia gravis]]
**[[Hyperviscosity syndrome]]
**[[Diffuse alveolar hemorrhage]] due to [[Goodpasture syndrome]]
**Chronic inflammatory demyelinating polyneuropathy
**Severe [[autoimmune hemolytic anemia]]
*Indications for which plasmapheresis is accepted second-line therapy:
**[[Lambert-Eaton myasthenic syndrome]]
**[[Multiple sclerosis]]: acute CNS demyelination unresponsive to steroids
**Rapidly progressive [[vasculitis]]
**Catastrophic thrombosis due to [[antiphospholipid syndrome]]
**Acute disseminated encephalomyelitis
**Severe [[systemic lupus erythematosus]]
**[[Multiple myeloma]] cast nephropathy
**RBC alloimmunization in pregnancy
**[[Mushroom Poisoning]]
**[[Hemolytic uremic syndrome]]
*Less established, possible indications
**[[Thyroid storm]] when antithyroid drugs ineffective or contraindicated
**[[Pemphigus vulgaris]] (severe and refractory to first-line management)
**[[Pyoderma gangrenosum]]

==Contraindications==
*Hemodynamic instability, sepsis, or other conditions causing inability to tolerate fluid shifts
*Inability to tolerate central line placement
*Allergy to [[FFP]] or albumin
*Severe [[hypocalcemia]] (citrate anticoagulant will precipitate calcium and worsen hypocalcemia)

==Equipment Needed==
*Dialysis or pheresis catheter
*[[Central line]] supplies
*Automated centrifuge or semipermeable membrane
*[[FFP]]

==Procedure==
*See [[central line]]
*Additional steps specific to device being used to apherese, consult specialist for this!

==Complications==
*[[Transfusion reactions]]
**[[Allergic transfusion reaction]]
**[[Transfusion-associated circulatory overload]] (TACO)
**[[Transfusion-related acute lung injury]] (TRALI)
**[[Transfusion-associated graft-versus-host disease]] (rare in plasma exchange)
**[[Fluid overload]]
**[[Sepsis]]
**[[Transfusion Infections]]
*Immunosupression
*[[Hypocalcemia]]
*Complications of [[central line]] placement

==See Also==
*[[Transfusion reaction]]

==External Links==

==References==
<references/>

[[Category:Procedures]]
[[Category:Heme/Onc]]

Plasmapheresis - Revision history

ClaireLewis: /* Indications */

ClaireLewis at 17:23, 1 October 2019

ClaireLewis: /* Complications */

ClaireLewis: Created page with "==Overview== *Involves extracorporeal separation of blood products, resulting in filtered plasma product *Patient's plasma is removed, blood cells re-infused, and (usually) do..."

ClaireLewis: Created page with "==Overview== Involves extracorporeal separation of blood products, resulting in filtered plasma product Patient's plasma is removed, blood cells re-infused, and (usually) do..."