Peptic ulcer disease - Revision history

Ostermayer: Prepared the page for translation

2026-01-04T23:51:54Z

Prepared the page for translation

Rossdonaldson1 at 23:37, 7 December 2022

2022-12-07T23:37:05Z

← Revisión anterior		Revisión del 23:37 7 dic 2022
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	[[File:Free air under diaphram.png\|thumb\|Free intra-abdominal air below the diaphragm (a complication of perforated ulcer).]]		[[File:Free air under diaphram.png\|thumb\|Free intra-abdominal air below the diaphragm (a complication of perforated ulcer).]]
	[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]		[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]

	===Work-Up===		===Work-Up===
	*CBC (rule out anemia)		*CBC (rule out anemia)

ClaireLewis: /* Non-Perforated */

2021-03-18T00:05:57Z

Non-Perforated

← Revisión anterior		Revisión del 00:05 18 mar 2021
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	*Stop [[NSAIDs]] and [[ETOH]]		*Stop [[NSAIDs]] and [[ETOH]]
	*[[PPI]]		*[[PPI]]
	**Generally heal ulcers faster than H2 blockers		**Generally heal ulcers faster than H2 blockers<ref>Walan A, Bader JP, Classen M, Lamers CB, Piper DW, Rutgersson K, Eriksson S. Effect of omeprazole and ranitidine on ulcer healing and relapse rates in patients with benign gastric ulcer. N Engl J Med. 1989 Jan 12;320(2):69-75. doi: 10.1056/NEJM198901123200201. PMID: 2643037.</ref>
	**[[Omeprazole]] 20-40mg QD		**[[Omeprazole]] 20-40mg QD
	*[[H2 blocker]]		*[[H2 blocker]]

Rossdonaldson1: /* Background */

2020-05-02T13:21:38Z

Background

← Revisión anterior		Revisión del 13:21 2 may 2020
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	[[File:Gray1046.png\|thumb\|Stomach anatomy]]		[[File:Gray1046.png\|thumb\|Stomach anatomy]]
	[[File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]		[[File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]
			[[File:Duodenumanatomy.jpg\|thumb\|Duodenum with major anatomical landmarks.]]
	[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]		[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]
	*Recurrent ulcerations in the stomach and proximal duodenum		*Recurrent ulcerations in the stomach and proximal duodenum

Rossdonaldson1: /* Background */

2020-05-02T13:19:08Z

Background

← Revisión anterior		Revisión del 13:19 2 may 2020
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	==Background==		==Background==
	[[File:Gray1046.png\|thumb\|Stomach anatomy]]		[[File:Gray1046.png\|thumb\|Stomach anatomy]]
	File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]		[[File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]
	[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]		[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]
	*Recurrent ulcerations in the stomach and proximal duodenum		*Recurrent ulcerations in the stomach and proximal duodenum

Rossdonaldson1: /* Background */

2020-05-02T13:18:54Z

Background

← Revisión anterior		Revisión del 13:18 2 may 2020
Línea 1:		Línea 1:
	==Background==		==Background==
	[[File:Gray1046.png\|thumb\|Stomach anatomy]]		[[File:Gray1046.png\|thumb\|Stomach anatomy]]
			File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]
	[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]		[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]
	*Recurrent ulcerations in the stomach and proximal duodenum		*Recurrent ulcerations in the stomach and proximal duodenum

Rossdonaldson1: /* Background */

2020-05-02T13:17:38Z

Background

← Revisión anterior		Revisión del 13:17 2 may 2020
Línea 1:		Línea 1:
	==Background==		==Background==
			[[File:Gray1046.png\|thumb\|Stomach anatomy]]
	[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]		[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]
	*Recurrent ulcerations in the stomach and proximal duodenum		*Recurrent ulcerations in the stomach and proximal duodenum
Línea 6:		Línea 7:
	**[[H. pylori]] found in 30-40% of U.S. population		**[[H. pylori]] found in 30-40% of U.S. population
	**[[NSAIDs]] inhibit prostaglandin synthesis (decreases mucus and bicarb production)		**[[NSAIDs]] inhibit prostaglandin synthesis (decreases mucus and bicarb production)
	*Perforation most commonly occurs in anterior wall of duodenum.		*Perforation most commonly occurs in anterior wall of duodenum.

	==Clinical Features==		==Clinical Features==

Rossdonaldson1: /* Complications */

2019-11-28T18:53:17Z

Complications

← Revisión anterior		Revisión del 18:53 28 nov 2019
Línea 77:		Línea 77:

	==Complications==		==Complications==
			*Perforation (see above)
	*Hemorrhage		*Hemorrhage
	**[[Upper GI Bleeding]]		**[[Upper GI Bleeding]]
	*Perforation (see above)		*[[SBO\|Obstruction]], due to:
	*[[SBO\|Obstruction]]
	*Occurs due to:
	**Scarring of gastric outlet		**Scarring of gastric outlet
	**Edema due to active ulcer		**Edema due to active ulcer

Rossdonaldson1: /* Evaluation */

2019-11-28T18:49:53Z

Evaluation

← Revisión anterior		Revisión del 18:49 28 nov 2019
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	==Evaluation==		==Evaluation==
	[[File:Free air under diaphram.png\|thumb\|Free intra-abdominal air below the diaphragm (a complication of perforated ulcer).]]		[[File:Free air under diaphram.png\|thumb\|Free intra-abdominal air below the diaphragm (a complication of perforated ulcer).]]
	~~[[File:PMC3813507 rjt07101.png\|thumb\|Free air under diaphragm (a complication of perforated ulcer).]]~~
	[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]		[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]
	===Work-Up===		===Work-Up===

Rossdonaldson1: /* Evaluation */

2019-11-28T18:49:38Z

Evaluation

← Revisión anterior		Revisión del 18:49 28 nov 2019
Línea 26:		Línea 26:

	==Evaluation==		==Evaluation==
			[[File:Free air under diaphram.png\|thumb\|Free intra-abdominal air below the diaphragm (a complication of perforated ulcer).]]
	[[File:PMC3813507 rjt07101.png\|thumb\|Free air under diaphragm (a complication of perforated ulcer).]]		[[File:PMC3813507 rjt07101.png\|thumb\|Free air under diaphragm (a complication of perforated ulcer).]]
	[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]		[[File:PMC3835032 1752-1947-7-257-2.png\|thumb\|Perforated duodenal ulcer presenting with a subphrenic abscess: (A) air-fluid collection (asterisk) with stranding (arrow). (B) air-fluid collection (asterisk) extends to the perihepatic space with extraluminal air bubbles (arrow).]]

← Revisión anterior		Revisión del 13:21 2 may 2020
Línea 2:		Línea 2:
	[[File:Gray1046.png\|thumb\|Stomach anatomy]]		[[File:Gray1046.png\|thumb\|Stomach anatomy]]
	[[File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]		[[File:Illu stomach2.jpg\|thumb\|Stomach wall anatomy]]
			[[File:Duodenumanatomy.jpg\|thumb\|Duodenum with major anatomical landmarks.]]
	[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]		[[File:Benign gastric ulcer 1.jpg\|thumb\|A benign gastric ulcer (from the antrum of a gastrectomy specimen).]]
	*Recurrent ulcerations in the stomach and proximal duodenum		*Recurrent ulcerations in the stomach and proximal duodenum