https://wikem.org/w/index.php?action=history&feed=atom&title=Pentoxifylline 2026-04-17T19:27:47Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Pentoxifylline&diff=122170&oldid=prev 2017-02-08T18:27:37Z

<p>Text replacement - &quot;--&gt;&quot; to &quot;→&quot;</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="es"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Revisión anterior</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revisión del 18:27 8 feb 2017</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l39">Línea 39:</td> <td colspan="2" class="diff-lineno">Línea 39:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Mechanism of Action==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Mechanism of Action==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*Inhibits phosphodiesterase, decreases plasma fibrinogen concentrations, and RBC/platelet <del style="font-weight: bold; text-decoration: none;">aggregation--&gt; </del>reduced blood viscosity, improved erythrocyte flexibility/microcirculatory flow</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*Inhibits phosphodiesterase, decreases plasma fibrinogen concentrations, and RBC/platelet <ins style="font-weight: bold; text-decoration: none;">aggregation→ </ins>reduced blood viscosity, improved erythrocyte flexibility/microcirculatory flow</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Comments==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Comments==</div></td></tr> </table>

Mholtz https://wikem.org/w/index.php?title=Pentoxifylline&diff=110501&oldid=prev 2016-11-14T00:45:54Z

<p>Created page with &quot;==Administration== *Type: *Dosage Forms: *Routes of Administration: Oral *Common Trade Names: Trental, Pentoxil ==Adult Dosing== *Intermittent claudication, stasis ulcer: 4...&quot;</p> <p><b>Página nueva</b></p><div>==Administration==<br /> *Type: <br /> *Dosage Forms:<br /> *Routes of Administration: Oral <br /> *Common Trade Names: Trental, Pentoxil<br /> <br /> ==Adult Dosing==<br /> *Intermittent claudication, stasis ulcer: 400mg PO TID<br /> *Vascular disorder of inner ear: 1600mg PO per day in 2-4 divided doses<br /> *Non-alcoholic fatty liver: 1200mg PO daily<br /> *Note: likely no benefit in acute alcoholic hepatitis&lt;ref&gt;Mathurin P, Louvet A, Duhamel A, et al. Prednisolone with vs without pentoxifylline and survival of patients with severe alcoholic hepatitis: a randomized clinical trial. JAMA. 2013;310(10):1033-41.&lt;/ref&gt;<br /> <br /> ==Pediatric Dosing==<br /> ''Safety/efficacy not established''<br /> <br /> ==Special Populations==<br /> *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C<br /> *[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out<br /> *Renal dosing: no adjustment<br /> *Hepatic dosing: no adjustment<br /> <br /> ==Contraindications==<br /> *Allergy to class/drug<br /> *Recent cerebral or retinal hemorrhage<br /> <br /> ==Adverse Reactions==<br /> ===Serious===<br /> *Aplastic anemia, thrombocytopenia<br /> *Angina<br /> *Jaundice<br /> *Retinal hemorrhage<br /> ===Common===<br /> *Nausea/vomiting<br /> <br /> ==Pharmacology==<br /> *Half-life: 0.4-1.6h<br /> *Metabolism: Hepatic<br /> *Excretion: <br /> <br /> ==Mechanism of Action==<br /> *Inhibits phosphodiesterase, decreases plasma fibrinogen concentrations, and RBC/platelet aggregation--&gt; reduced blood viscosity, improved erythrocyte flexibility/microcirculatory flow<br /> <br /> ==Comments==<br /> <br /> ==See Also==<br /> <br /> ==References==<br /> &lt;references/&gt;<br /> [[Category:Pharmacology]]</div>

ClaireLewis