Oxacillin - Revision history

Danbot: Add AntibioticDose SMW query table for dynamic indications by disease

2026-03-20T20:38:24Z

Add AntibioticDose SMW query table for dynamic indications by disease

@@ Línea 20: / Línea 20: @@
 *2g IV q4 hours
 *Examples: brain abscess, [[bursitis]], [[erysipelas]], [[mastitis]], mastoiditis, [[osteomyelitis]], perinephric abscess, [[pneumonia]], pyomyositis, Scalded Skin Syndrome, [[Toxic Shock Syndrome]]
 ==Pediatric Dosing==
 ===General===
 *Mild-to-moderate

2025-07-18T17:41:20Z

← Revisión anterior		Revisión del 17:41 18 jul 2025
Línea 1:		Línea 1:
	==General==		==General==
	*Type: Anti-Staphylococcal [[Is DrugClass::Penicillin]]		*Type: [[Is PenicillinType::Anti-Staphylococcal]] [[Is DrugClass::Penicillin]]
	*Dosage Forms: IM; IV		*Dosage Forms: IM; IV
	*Common Trade Names: Bactocill		*Common Trade Names: Bactocill

2025-07-18T17:15:16Z

← Revisión anterior		Revisión del 17:15 18 jul 2025
Línea 1:		Línea 1:
	==General==		==General==
	*Type: Anti-Staphylococcal [[Penicillin]]		*Type: Anti-Staphylococcal [[Is DrugClass::Penicillin]]
	*Dosage Forms: IM; IV		*Dosage Forms: IM; IV
	*Common Trade Names: Bactocill		*Common Trade Names: Bactocill

2019-09-23T00:48:58Z

References

2017-08-30T22:58:21Z

← Revisión anterior		Revisión del 22:58 30 ago 2017
Línea 2:		Línea 2:
	*Type: Anti-Staphylococcal [[Penicillin]]		*Type: Anti-Staphylococcal [[Penicillin]]
	*Dosage Forms: IM; IV		*Dosage Forms: IM; IV
	*Common Trade Names:		*Common Trade Names: Bactocill

	==Adult Dosing==		==Adult Dosing==
Línea 209:		Línea 209:
	*[[Antibiotics]]		*[[Antibiotics]]

	==~~Source~~==		==References==

	<references/>		<references/>

	[[Category:Pharmacology]]		[[Category:Pharmacology]]

2017-08-15T17:37:01Z

Added pharmacology and renal dosing information and cautions

← Revisión anterior		Revisión del 17:37 15 ago 2017
Línea 41:		Línea 41:
	*Lactation: Use caution		*Lactation: Use caution
	*Renal Dosing		*Renal Dosing
	**Adult		**Adult: No adjustment
	**Pediatric		**Pediatric:
			***CrCl <10: Use lower end of dosing range
	*Hepatic Dosing		*Hepatic Dosing
	**Adult		**Adult: Not defined
	**Pediatric		**Pediatric: Not defined

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Caution:
			**Non-anaphylactic hypersensitivity to beta-lactams
			**Hypersensitivity to corn
			**[[Asthma]]
			**Recent abx-associated colitis
			**Renal impairment
			**Sodium restriction
			**Seizure disorder

	==Adverse Reactions==		==Adverse Reactions==
Línea 71:		Línea 80:
	==Pharmacology==		==Pharmacology==
	*Half-life: 20-60 minutes (prolonged in neonates and renal impairment)		*Half-life: 20-60 minutes (prolonged in neonates and renal impairment)
	*Metabolism:		*Metabolism: Liver 45%; active metabolite
	*Excretion:		*Excretion: Urine (55-60% unchanged), Bile 10%
	*Mechanism of Action:		*Mechanism of Action: Bactericidal; inhibits cell wall mucopeptide synthesis

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==

2016-09-22T06:15:27Z

Source

2016-07-21T11:35:58Z

Text replacement - "6 mg" to "6mg"

← Revisión anterior		Revisión del 11:35 21 jul 2016
Línea 34:		Línea 34:
	===Community-Acquired [[Pneumonia]] (>3 Months)<ref>IDSA/PIDS, 2011</ref>===		===Community-Acquired [[Pneumonia]] (>3 Months)<ref>IDSA/PIDS, 2011</ref>===
	*150-200mg/kg/day divided q6-8 hours		*150-200mg/kg/day divided q6-8 hours
	*First Dose: 37.5-66.~~6 mg~~/kg IV x 1		*First Dose: 37.5-66.6mg/kg IV x 1
	*For [[MSSA]]		*For [[MSSA]]

2016-07-21T08:06:22Z

Text replacement - "0 mg" to "0mg"

← Revisión anterior		Revisión del 08:06 21 jul 2016
Línea 7:		Línea 7:
	===General===		===General===
	*Mild-to-moderate infection		*Mild-to-moderate infection
	**250-~~500 mg~~ IM/IV q4-6 hours		**250-500mg IM/IV q4-6 hours
	*Severe infection		*Severe infection
	**1g IM/IV q4-6 hours		**1g IM/IV q4-6 hours
Línea 24:		Línea 24:
	===General===		===General===
	*Mild-to-moderate		*Mild-to-moderate
	**~~50 mg~~/kg/day IM/IV divided q6 hours		**50mg/kg/day IM/IV divided q6 hours
	**First Dose: 12.5mg/kg IM/IV x 1		**First Dose: 12.5mg/kg IM/IV x 1
	**Max: 4 g/day		**Max: 4 g/day
	*Severe		*Severe
	**~~100 mg~~/kg/day IM/IV divided q4-6 hours		**100mg/kg/day IM/IV divided q4-6 hours
	**First Dose: 16.6-25mg/kg IM/IV x 1		**First Dose: 16.6-25mg/kg IM/IV x 1
	**Max: 12 g/day		**Max: 12 g/day

	===Community-Acquired [[Pneumonia]] (>3 Months)<ref>IDSA/PIDS, 2011</ref>===		===Community-Acquired [[Pneumonia]] (>3 Months)<ref>IDSA/PIDS, 2011</ref>===
	*150-~~200 mg~~/kg/day divided q6-8 hours		*150-200mg/kg/day divided q6-8 hours
	*First Dose: 37.5-66.6 mg/kg IV x 1		*First Dose: 37.5-66.6 mg/kg IV x 1
	*For [[MSSA]]		*For [[MSSA]]

2016-07-20T03:52:18Z

Text replacement - "5 mg" to "5mg"