Opsoclonus - Revision history

Rossdonaldson1 at 23:40, 17 November 2021

2021-11-17T23:40:32Z

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	==External Links==		==External Links==
	[http://www.nejm.org/doi/full/10.1056/NEJMicm1002035 NEJM Opsoclonus ]		*[http://www.nejm.org/doi/full/10.1056/NEJMicm1002035 NEJM Opsoclonus ]

	==References==		==References==

2021-11-17T23:37:22Z

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	==Background==		==Background==
	~~Opsoclonus is~~ involuntary, irregular multidirectional saccadic eye movements. ~~It occurs~~ at fixed gaze and has been reported with various medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>		*Definition: involuntary, irregular multidirectional saccadic eye movements.<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>
			*Occurs at fixed gaze and has been reported with various medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>

	==Clinical Features==		==Clinical Features==

2016-12-11T02:31:43Z

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	==References==		==References==
	<references/>		<references/>

			[[Category:Ophthalmology]] [[Category:Toxicology]]

2016-11-24T03:14:53Z

Background

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	==Background==		==Background==
	Opsoclonus is involuntary, irregular multidirectional saccadic eye movements. It occurs at fixed gaze and has been reported with ~~ingestion of many~~ medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>		Opsoclonus is involuntary, irregular multidirectional saccadic eye movements. It occurs at fixed gaze and has been reported with various medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>

	==Clinical Features==		==Clinical Features==
	*Multidirectional involuntary eye movements when at fixed gaze		*Multidirectional involuntary eye movements when at fixed gaze

2016-11-24T03:05:56Z

Clinical Features

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	Opsoclonus is involuntary, irregular multidirectional saccadic eye movements. It occurs at fixed gaze and has been reported with ingestion of many medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>		Opsoclonus is involuntary, irregular multidirectional saccadic eye movements. It occurs at fixed gaze and has been reported with ingestion of many medication overdoses such as [[organophosphates]], [[lithium]], cetirizine, amitryptiline, and [[diphenhydramine]].<ref> Carstairs S. et al. Opsoclonus Due to Diphenhydramine Poisoning. N Engl J Med 2010; 363:e40</ref>
	==Clinical Features==		==Clinical Features==
	*Multidirectional eye movements when at fixed gaze		*Multidirectional involuntary eye movements when at fixed gaze

	==Differential Diagnosis==		==Differential Diagnosis==
	{{Differential diagnosis nystagmus}}		{{Differential diagnosis nystagmus}}

2016-11-24T03:05:28Z

External Links

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	==External Links==		==External Links==
			[http://www.nejm.org/doi/full/10.1056/NEJMicm1002035 NEJM Opsoclonus ]

	==References==		==References==
	<references/>		<references/>

2016-11-24T03:04:38Z

2016-11-24T03:03:46Z

Evaluation

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	{{Differential diagnosis nystagmus}}		{{Differential diagnosis nystagmus}}
	==Evaluation==		==Evaluation==
	~~{{Vertigo workup}}~~		Evaluation for symptoms of [[vertigo]], [[CVA]], and due to the association with medication overdoses, a psychiatric screening is worth consideration
			#Glucose check
			#Full neuro exam
			#TM exam
			#CTA or MRA (diagnostic study of choice) of the neck/brain if symptoms consistent with central cause

	==Management==		==Management==

2016-11-24T03:02:00Z

Evaluation

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	{{Differential diagnosis nystagmus}}		{{Differential diagnosis nystagmus}}
	==Evaluation==		==Evaluation==
			{{Vertigo workup}}

	==Management==		==Management==

2016-11-24T02:57:26Z

Disposition

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	==Disposition==		==Disposition==
			Generally patients are admitted if the etiology is due to an overdose and further supportive care and psychiatric monitoring is required.

	==See Also==		==See Also==