Morganella morganii - Revision history

Ostermayer: /* Clinical Features */

2026-01-28T19:01:08Z

Clinical Features

← Revisión anterior		Revisión del 19:01 28 ene 2026
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	**Often associated with long-term indwelling urinary catheters		**Often associated with long-term indwelling urinary catheters
	**Urease-producing organism (leads to alkaline urine and Struvite stone/Staghorn calculi formation)		**Urease-producing organism (leads to alkaline urine and Struvite stone/Staghorn calculi formation)
	**[[~~Colored urine\|~~Purple urine bag syndrome]] (rare, but classic association)		**[[Purple urine bag syndrome]] (rare, but classic association)
	*[[Skin and Soft Tissue Infection]]		*[[Skin and Soft Tissue Infection]]
	**Surgical site infections		**Surgical site infections

Ostermayer: /* Evaluation */

2026-01-28T19:00:49Z

Evaluation

← Revisión anterior		Revisión del 19:00 28 ene 2026
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	*[[CBC]]: Leukocytosis		*[[CBC]]: Leukocytosis
	*[[Lactate]]: Elevated in sepsis		*[[Lactate]]: Elevated in sepsis
	*[[Blood Cx]]: Mandatory if febrile or hypothermic		*[[Blood cultures]]: Mandatory if febrile or hypothermic
	*Imaging:		*Imaging:
	**[[CT ~~KUB]]~~ if concern for struvite stones/obstruction		**CT if concern for struvite stones/obstruction
	**[[CT Soft Tissue]] if concern for necrotizing fasciitis (snake bite/wound)		**CT with IV contrast Soft Tissue if concern for [[necrotizing fasciitis]] (snake bite/wound)

	==Management==		==Management==

Ostermayer: /* Management */

2026-01-28T18:47:39Z

Management

← Revisión anterior		Revisión del 18:47 28 ene 2026
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	**Remove/replace indwelling urinary catheter		**Remove/replace indwelling urinary catheter
	**Debridement of infected wounds/bites		**Debridement of infected wounds/bites
	*Antibiotic considerations relating to '''beta$-lactamase'''		*Antibiotic considerations relating to '''beta-lactamase'''
	**Intrinsic resistance to many beta-lactams		**Intrinsic resistance to many beta-lactams
	**Avoid first/second generation cephalosporins and ampicillin		**Avoid first/second generation cephalosporins and ampicillin

Ostermayer: /* Management */

2026-01-28T18:47:27Z

Management

← Revisión anterior		Revisión del 18:47 28 ene 2026
Línea 37:		Línea 37:
	**Remove/replace indwelling urinary catheter		**Remove/replace indwelling urinary catheter
	**Debridement of infected wounds/bites		**Debridement of infected wounds/bites
	*Antibiotic considerations relating to '''~~AmpC $\~~beta$-lactamase'''		*Antibiotic considerations relating to '''beta$-lactamase'''
	**Intrinsic resistance to many $\beta$-lactams		**Intrinsic resistance to many beta-lactams
	**Avoid first/second generation cephalosporins and ampicillin		**Avoid first/second generation cephalosporins and ampicillin
	**Inducible resistance may occur with 3rd generation cephalosporins (Ceftriaxone)		**Inducible resistance may occur with 3rd generation cephalosporins (Ceftriaxone)

Ostermayer: /* Clinical Features */

2026-01-28T18:46:51Z

Clinical Features

← Revisión anterior		Revisión del 18:46 28 ene 2026
Línea 10:		Línea 10:
	**Most common presentation		**Most common presentation
	**Often associated with long-term indwelling urinary catheters		**Often associated with long-term indwelling urinary catheters
	**Urease-producing organism (leads to alkaline urine and [[Struvite stone]]/Staghorn calculi formation)		**Urease-producing organism (leads to alkaline urine and Struvite stone/Staghorn calculi formation)
	**[[Purple urine bag syndrome]] (rare, but classic association)		**[[Colored urine\|Purple urine bag syndrome]] (rare, but classic association)
	*[[Skin and Soft Tissue Infection]]		*[[Skin and Soft Tissue Infection]]
	**Surgical site infections		**Surgical site infections

Ostermayer at 17:22, 28 January 2026

2026-01-28T17:22:03Z

← Revisión anterior		Revisión del 17:22 28 ene 2026
Línea 2:		Línea 2:
	*Gram-negative, facultative anaerobic rod		*Gram-negative, facultative anaerobic rod
	*Member of the tribe Proteeae (along with ''Proteus'' and ''Providencia'')		*Member of the tribe Proteeae (along with ''Proteus'' and ''Providencia'')
	*Important cause of nosocomial infections, particularly ~~[[Catheter~~-associated urinary tract ~~infection\|CAUTIs]]~~		*Important cause of nosocomial infections, particularly catheter-associated urinary tract infections
	*Typically affects immunocompromised, elderly, or nursing home residents		*Typically affects immunocompromised, elderly, or nursing home residents
	*Possesses chromosomal AmpC $\beta$-lactamase (inducible resistance)

	==Clinical Features==		==Clinical Features==

Ostermayer: Created page with "==Background== Gram-negative, facultative anaerobic rod Member of the tribe Proteeae (along with ''Proteus'' and ''Providencia'') Important cause of nosocomial infections, particularly CAUTIs Typically affects immunocompromised, elderly, or nursing home residents Possesses chromosomal AmpC $\beta$-lactamase (inducible resistance) ==Clinical Features== Urinary Tract Infection Most common presentation Often ass..."

2026-01-28T01:02:53Z

Created page with "==Background== *Gram-negative, facultative anaerobic rod *Member of the tribe Proteeae (along with ''Proteus'' and ''Providencia'') *Important cause of nosocomial infections, particularly CAUTIs *Typically affects immunocompromised, elderly, or nursing home residents *Possesses chromosomal AmpC $\beta$-lactamase (inducible resistance) ==Clinical Features== *Urinary Tract Infection **Most common presentation **Often ass..."

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==Background==
*Gram-negative, facultative anaerobic rod
*Member of the tribe Proteeae (along with ''Proteus'' and ''Providencia'')
*Important cause of nosocomial infections, particularly [[Catheter-associated urinary tract infection|CAUTIs]]
*Typically affects immunocompromised, elderly, or nursing home residents
*Possesses chromosomal AmpC $\beta$-lactamase (inducible resistance)

==Clinical Features==
*[[Urinary Tract Infection]]
**Most common presentation
**Often associated with long-term indwelling urinary catheters
**Urease-producing organism (leads to alkaline urine and [[Struvite stone]]/Staghorn calculi formation)
**[[Purple urine bag syndrome]] (rare, but classic association)
*[[Skin and Soft Tissue Infection]]
**Surgical site infections
**'''Snake bites''' (Common isolate in oral flora of snakes, infections secondary to cobra/viper bites)
*[[Sepsis]]/[[Bacteremia]]
**High mortality rate with inadequate initial antibiotic coverage due to resistance profile
*[[Meningitis]]
**Rare, typically nosocomial or secondary to brain abscess/otogenic infection
*[[Chorioamnionitis]] (Rare)

==Differential Diagnosis==
{{Dysuria DDX}}

==Evaluation==
*[[Urinalysis]]: Alkaline pH (often > 7.5 due to urease)
*[[CBC]]: Leukocytosis
*[[Lactate]]: Elevated in sepsis
*[[Blood Cx]]: Mandatory if febrile or hypothermic
*Imaging:
**[[CT KUB]] if concern for struvite stones/obstruction
**[[CT Soft Tissue]] if concern for necrotizing fasciitis (snake bite/wound)

==Management==
*Source control
**Remove/replace indwelling urinary catheter
**Debridement of infected wounds/bites
*Antibiotic considerations relating to '''AmpC $\beta$-lactamase'''
**Intrinsic resistance to many $\beta$-lactams
**Avoid first/second generation cephalosporins and ampicillin
**Inducible resistance may occur with 3rd generation cephalosporins (Ceftriaxone)
*Preferred agents: [[Carbapenems]], [[Cefepime]], [[Fluoroquinolones]], or [[Aminoglycosides]]

==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy</ref>==
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Category'''
| align="center" style="background:#f0f0f0;"|'''Antibiotic'''
| align="center" style="background:#f0f0f0;"|'''Sensitivity'''
|-
| [[Penicillins]]||[[Penicillin G]]||R
|-
| ||[[Penicillin V]]||R
|-
| Anti-Staphylocccal [[Penicillins]]||[[Methicillin]]||R
|-
| ||[[Nafcillin]]/[[Oxacillin]]||R
|-
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||R
|-
| ||[[Amox-Clav]]||R
|-
| ||[[AMP-Sulb]]||R
|-
| Anti-Pseudomonal [[Penicillins]]||[[Ticarcillin]]||S
|-
| ||[[Pip-Tazo]]||'''S'''
|-
| ||[[Piperacillin]]||'''S'''
|-
| [[Carbapenems]]||[[Doripenem]]||'''S'''
|-
| ||[[Ertapenem]]||'''S'''
|-
| ||[[Imipenem]]||'''S'''
|-
| ||[[Meropenem]]||'''S'''
|-
| ||[[Aztreonam]]||'''S'''
|-
| [[Fluoroquinolones]]||[[Ciprofloxacin]]||'''S'''
|-
| ||[[Levofloxacin]]||'''S'''
|-
| ||[[Moxifloxacin]]||'''S'''
|-
| 1st G [[Cephalo]]||[[Cefazolin]]||R
|-
| ||[[Cephalexin]]||R
|-
| 2nd G. [[Cephalo]]||[[Cefotetan]]||R
|-
| ||[[Cefoxitin]]||R
|-
| ||[[Cefuroxime]]||R
|-
| 3rd G. [[Cephalo]]||[[Cefotaxime]]||X1
|-
| ||[[CefTRIAXone]]||X1
|-
| ||[[CefTAZidime]]||'''S'''
|-
| ||[[Cefdinir]]||X1
|-
| 4th G. [[Cephalo]]||[[Cefepime]]||'''S'''
|-
| [[Aminoglycosides]]||[[Gentamicin]]||'''S'''
|-
| ||[[Tobramycin]]||'''S'''
|-
| ||[[Amikacin]]||'''S'''
|-
| ||[[Clindamycin]]||R
|-
| [[Macrolides]]||[[Erythromycin]]||R
|-
| ||[[Azithromycin]]||R
|-
| Tetracyclines||[[Doxycycline]]||X1
|-
| ||[[Tigecycline]]||R
|-
| Glyco/Lipoglycopeptides||[[Vancomycin]]||R
|-
| ||[[Daptomycin]]||R
|-
| Urinary Agents||[[Nitrofurantoin]]||R
|-
| ||[[Fosfomycin]]||R
|-
| Other||[[Trimethoprim]]||R
|-
| ||[[TMP-SMX]]||'''S'''
|-
| ||[[Metronidazole]]||R
|-
| ||[[Linezolid]]||R
|-
| ||[[Colistimethate]]||R
|-
| ||[[Polymyxin B]]||R
|}

===Key===
{{Template:Antibacterial Spectra Key}}
*'''Note:''' ''Morganella'' has intrinsic resistance to Oxacillin, Ampicillin, Amoxicillin, most 1st/2nd Gen Cephalosporins, Macrolides, Lincosamides, Glycopeptides, Nitrofurantoin, and '''Polymyxins (Colistin)'''.

==Table Overview==
{{Clinically Relevant Bacteria}}

==See Also==
*[[Microbiology (Main)]]
*[[Urinary Tract Infection]]
*[[Snake bites]]

==References==
<references/>

[[Category:ID]]