Mold toxicity - Revision history

ClaireLewis: /* References */

2019-09-28T19:32:04Z

References

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	[[Category:Environmental]]		[[Category:Environmental]]
			[[Category:ID]]

Rossdonaldson1: /* Mechanism of Toxicity */

2017-01-04T04:11:39Z

Mechanism of Toxicity

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	*Allergy		*Allergy
	**More commonly outdoor molds cause allergy but they can be found indoors in cases of excessive water damage		**More commonly outdoor molds cause allergy but they can be found indoors in cases of excessive water damage
	*Infection		*[[Fungal infections\|Infection]]
	**Only a few fungi can infect immunocompetent people: Coccidioides, Blastomyces, Histoplasma, Cryptococcus		**Only a few fungi can infect immunocompetent people: [[Coccidioides]], [[Blastomyces]], [[Histoplasma]], [[Cryptococcus]]
	**Immunocompromised people are at significant risk even from Candida and Aspergillus		**Immunocompromised people are at significant risk even from [[Candida]] and [[Aspergillus]]
	*Toxicity		*Toxicity
	**Glucans, a component of the cell wall, can produce Organic Dust Toxic Syndrome when inhaled		**Glucans, a component of the cell wall, can produce Organic Dust Toxic Syndrome when inhaled

Rossdonaldson1: /* Common Household Molds */

2017-01-04T04:09:57Z

Common Household Molds

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	===Common Household Molds===		===Common Household Molds===
	**Penicillium		*Penicillium
	**Cladosporium		*Cladosporium
	**[[Aspergillus]]		*[[Aspergillus]]
	**Alternaria		*Alternaria

	===Mechanism of Toxicity===		===Mechanism of Toxicity===

Rossdonaldson1 at 04:09, 4 January 2017

2017-01-04T04:09:18Z

← Revisión anterior		Revisión del 04:09 4 ene 2017
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	==Background==		==Background==
	*Molds are multicellular fungi that decompose organic matter		*Molds are multicellular fungi that decompose organic matter
	*Common ~~household molds:~~
			===Common Household Molds===
	**Penicillium		**Penicillium
	**Cladosporium		**Cladosporium

Rossdonaldson1: /* References */

2017-01-04T04:08:04Z

References

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	==Disposition==		==Disposition==
	*Outpatient management		*Outpatient management

			==See Also==
			*[[Fungal infections]]

	==References==		==References==

Rossdonaldson1: /* Differential Diagnosis */

2017-01-04T04:05:43Z

Differential Diagnosis

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	*[[Asthma]]		*[[Asthma]]
	*Allergic rhinitis		*Allergic rhinitis

			{{ILI DDX}}

	==Evaluation==		==Evaluation==

Rossdonaldson1: /* Differential Diagnosis */

2017-01-04T04:04:59Z

Differential Diagnosis

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	==Differential Diagnosis==		==Differential Diagnosis==
			*[[Acute allergic reaction]]
			*[[Pneumonia]]
			*[[Asthma]]
			*Allergic rhinitis

	==Evaluation==		==Evaluation==

Rossdonaldson1: /* Clinical Features */

2017-01-04T04:04:19Z

Clinical Features

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	==Clinical Features==		==Clinical Features==
	===Mold Allergy===		===Mold Allergy===
	**IgE antibodies against molds can lead to asthma or allergic rhinitis		*IgE antibodies against molds can lead to asthma or allergic rhinitis
	**Hypersensitivity pneumonitis is a rare immune response to high concentrations of fungal proteins		*Hypersensitivity pneumonitis is a rare immune response to high concentrations of fungal proteins

	===Organic Dust Toxic Syndrome===		===Organic Dust Toxic Syndrome===

Rossdonaldson1 at 04:03, 4 January 2017

2017-01-04T04:03:28Z

← Revisión anterior		Revisión del 04:03 4 ene 2017
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	**Penicillium		**Penicillium
	**Cladosporium		**Cladosporium
	**Aspergillus		**[[Aspergillus]]
	**Alternaria		**Alternaria

	==Mechanism of Toxicity==		===Mechanism of Toxicity===
	*Allergy		*Allergy
	**More commonly outdoor molds cause allergy but they can be found indoors in cases of excessive water damage		**More commonly outdoor molds cause allergy but they can be found indoors in cases of excessive water damage
Línea 17:		Línea 17:

	==Clinical Features==		==Clinical Features==
	*Mold Allergy		===Mold Allergy===
	**IgE antibodies against molds can lead to asthma or allergic rhinitis		**IgE antibodies against molds can lead to asthma or allergic rhinitis
	**Hypersensitivity pneumonitis is a rare immune response to high concentrations of fungal proteins		**Hypersensitivity pneumonitis is a rare immune response to high concentrations of fungal proteins
	*Organic Dust Toxic Syndrome
	**flu-like illness between 4-8 hours after heavy exposure to mold		===Organic Dust Toxic Syndrome===
	**Symptoms are self-limited and resolve in 24 hours		*[[flu-like illness]] between 4-8 hours after heavy exposure to mold
	*Sick Building Syndrome		*Symptoms are self-limited and resolve in 24 hours
	**Vague constellation of neurologic, dermatologic, gastrointestinal, and respiratory complaints attributed to a building's environment
			===Sick Building Syndrome===
			*Vague constellation of neurologic, dermatologic, gastrointestinal, and respiratory complaints attributed to a building's environment

			==Differential Diagnosis==

	==Evaluation==		==Evaluation==
			*Generally, no specific workup in the ED
			**May workup specific symptoms, if deemed appropriate

			===Outpatient===
			Consider:
	*RAST (Radioallergosorbent) testing can detect IgE mediated allergy		*RAST (Radioallergosorbent) testing can detect IgE mediated allergy
	*Air samples and "bulk, wipe, and wall" samples can detect presence of molds		*Air samples and "bulk, wipe, and wall" samples can detect presence of molds
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	==Management==		==Management==
	*No Specific drugs or antidotes		*No Specific drugs or antidotes
	*Decontamination of environment		*Decontamination and avoidance of environment

			==Disposition==
			*Outpatient management

	==References==		==References==

Rossdonaldson1: Rossdonaldson1 moved page Molds to Mold toxicity

2017-01-04T04:00:57Z

Rossdonaldson1 moved page Molds to Mold toxicity

← Revisión anterior	Revisión del 04:00 4 ene 2017
(Sin diferencias)